Skip to main content
OpenTrials
Completed

NCT Number: NCT01457651

Comparison of Four Different Recruitment Maneuvers in Patients After Coronary Surgery

The risk of respiratory failure after cardiac surgery is high, and it may result in many complications. The maneuver of alveolar recruitment may improve the oxygen transport in the human organism. The investigators compare three different types of alveolar recruitment in patient after cardiac surgery, to reveal which one is better.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hypoxemia Hypoxia Pathological Conditions, Signs and Symptoms Recruitment Signs and Symptoms Signs and Symptoms, Respiratory

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

City hospital # 1

Arkhangelsk, Arkhangelskaya oblast, 163000, Russia

About this study

The study compares three different approaches to alveolar recruitment maneuvers in the immediate postoperative period after off-pump coronary bypass grafting.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 and 75
  • Off-pump coronary artery bypass grafting
  • Possibility to discontinue respiratory support in the first day after intervention

Exclusion criteria

  • Signs of ARDS
  • COPD in decompensation phase
  • Requirement for inotropic support(epinephrine >0,1 mcg/kg/hr)
  • Bronchiectases
  • Pregnancy
  • Morbid obesity
  • Aortic aneurism
  • AMI in previous month

Treatment and study plan

alveolar recruitment

Procedure

Four approaches:

  • CPAP 40 cm H2O
  • Peak pressure 40 cm H2O
  • PEEP 15 cm H2O for 300 sec
  • no intervention (controls)

Other names: CPAP40, PEAK40, PEEP15, CONTROLS

Primary outcomes

  1. Respiratory support

    Time frame: 24 hrs

    The duration of the postoperative respiratory support

Secondary outcomes

  1. The incidence of postoperative atelectasis

    Time frame: 24 hrs

    Incidence of atelectases during 24 hrs

  2. Incidence of reintubation

    Time frame: 24 Hrs

  3. Oxygenation

    Time frame: 12 hrs after extubation

    Changes in PaO2/FiO2 ratio

  4. Length of ICU and hospital stay

    Time frame: 28 Days

    Length of ICU and hospital stay

Sponsors and collaborators

Lead sponsor

Northern State Medical University

Other

Collaborators

  • Regional hospital of Arkhangelsk

Registry information

Official study title

Comparison of Different Types of Postoperative Pulmonary Recruitment and Predicting Its Efficacy Following Off-pump Coronary Artery Bypass Grafting

Acronym: RECR-CABG

Important dates

Study start
2010
Primary completion
2011
Study completion
2012
First posted
Oct 24, 2011
Registry last updated
Jun 25, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.