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Completed

NCT Number: NCT00165958

Comparison of Excision Versus Punch Incision in the Treatment of Epidermal Cysts

The purpose of this trial is to compare two standard of care treatments for removing epidermal cysts. Surgical excision removes the entire cyst but requires a larger hole in the skin. A punch incision makes a smaller hole through which the cyst can be removed. The trial's purpose is to determine if one method is better than another in terms of recurrence, infection, or other side effects.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Atlanta VA Medical Center

Decatur, Georgia, 30322, United States

About this study

The purpose of this trial is to compare two standard of care treatments for removing epidermal cysts. Surgical excision removes the entire cyst but requires a larger hole in the skin. A punch incision makes a smaller hole through which the cyst can be removed. The trial's purpose is to determine if one method is better than another in terms of recurrence, infection, or other side effects.

Patients with epidermal cysts will be randomized to having the cyst removed by surgical excision or by a smaller punch incision followed by removal of the cyst through the smaller hole. The skin will be stitched shut in both cases. A short survey about how the cyst affects the patient will be given before the cyst is removed. When the stitches are removed 2 weeks later, photographs will be taken and a survey regarding satisfaction with the procedure will be given. Two additional phone surveys, given at 4 and 12 months after the procedure, wil be given to ask about recurrence, satisfaction with the procedure, side effects, and how the cyst affected the patient's life. The study doctor will be blinded as to which procedure each subject underwent. Forty subjects will be recruited at the Atlanta Veteran's Administration Medical Center

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult 18 years or older
  • Epidermal cyst 1-3 cm in diameter on the trunk

Exclusion criteria

  • Infected cyst requiring systemic antibiotics
  • Pregnant females
  • Unable to return to clinic for suture removal
  • Previous excision of target cyst

Treatment and study plan

Excisional surgery of epidermal cyst

Procedure

Traditional extirpation of cyst en toto

Punch incision of epidermal cyst

Procedure

removal of cyst first with incisional effort with a punch biopsy tool

Primary outcomes

  1. Number of Participants With Cyst Recurrence

    Time frame: 16 months

    Recurrence of cyst after removal

Sponsors and collaborators

Lead sponsor

Emory University

Other

Registry information

Important dates

Study start
2005
Primary completion
2008
Study completion
2011
First posted
Sep 14, 2005
Registry last updated
Aug 4, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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