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OpenTrials
Completed

NCT Number: NCT00791908

Comparison of Electrodessication, Potassium Titanyl Phosphate (KTP) Laser and Pulsed Dye Laser for Treatment of Cherry Angiomata

The primary objective of this study is to determine whether laser treatments over 6 weeks using the pulsed dye laser system or the potassium titanyl phosphate (KTP) laser are effective in patients with cherry angiomas as observed by a physician provider and the subject.

The investigators hypothesize that the two laser treatments will be an effective tool for treating cherry angiomas. The investigators aim to compare these modalities to electrodessication, as all three modalities are considered the current standard of care. Electrodessication can result in atrophic lesions at the site of the treated cherry angiomas.

In summary, the goal of this project is to compare the non-ablative pulsed dye laser and the AuraTM potassium titanyl phosphate (KTP) laser to each other and to the current standard of care, electrodessication.

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Key information

Conditions

Cherry Angioma

Age range

18 year–95 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Northwestern University

Chicago, Illinois, 60611, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 to 95 years.
  • Have at least 12 cherry angiomas (4 per each third of the torso) that have been documented.
  • The subjects are in medically stable condition.
  • The subject has willingness and the ability to understand and provide informed consent for the procedure and is able to communicate with the investigator.
  • Must be willing not to employ other treatment options for cherry angiomas during the course of this study.

Exclusion criteria

  • Under 18 years of age and over 95 years of age
  • Pregnancy or lactation.
  • Subjects who are unable to understand the protocol or to give informed consent.
  • Subjects cannot have had previous laser treatment in the last 6 months before enrollment.
  • Subjects have a cardiac defibrillator or pacemakers that may interact with the electrodesiccation technique.
  • Subjects have no serious medical conditions that would contradict participation in the research.

Treatment and study plan

Electrodessication

Procedure

Treatment applied to a third of the torso at each study visit.

Pulsed dye laser (PDL)

Procedure

Laser treatment applied to a third of the torso at each study visit.

potassium titanyl phosphate (KTP)

Procedure

Laser treatment applied to a third of the torso at each study visit.

Primary outcomes

  1. Mean Changes in Color, Texture, and Size of Cherry Angiomata From Baseline to 3 Months After the Second Treatment by Treatment Type as Assessed by Blinded Raters

    Time frame: Baseline and 3 months

    Each subject received all 3 treatments. Serial standardized photographs evaluated for color,texture and size by 2 blinded dermatologists using ordinal visual analog scales from 0 to 10(color: 0=skin colored, 5=red, 10=purple; texture: 0=flat, 5=mildly elevated, 10=elevated; size: 0=0mm, 10=10 mm).

Sponsors and collaborators

Lead sponsor

Northwestern University

Other

Registry information

Important dates

Study start
2006
Primary completion
2007
Study completion
2007
First posted
Nov 17, 2008
Registry last updated
Mar 6, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.