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Recruiting

NCT Number: NCT07016360

Comparison of Efficacy of Topical Adaplene Gel Versus Crythotherapy in Recurrent Plantar Warts

This is a comparative study between two treatment options for skin viral infection.

Recruiting

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Key information

Conditions

Viral Warts DNA Virus Infections Infections Papillomavirus Infections Skin Diseases Skin Diseases, Infectious Skin Diseases, Viral Skin and Connective Tissue Diseases Tumor Virus Infections Virus Diseases Warts

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Khyber Teaching Hospital

Peshawar, Khyber Pakhtunkhwa, 25000, Pakistan

Location status: Recruiting

About this study

This is a comparative study between two treatment for viral infection in epidermal layer of skin that proliferates slowly forming thick, growths. This study will compare and evaluate the differences in efficacy between topical liquid nitrogen and topical retinoids.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

-

Patients age limit 18-60 Years Patients with either gender (Male/Female) Patients with recurrent plantar warts

Exclusion criteria

  • Pregnancy/lactation. Pt on topical or systemic therapy in last 6 months. On immunosuppressants. > 5 lesions. Pts with local secondary infections.

Treatment and study plan

Topical Adapalene Gel 0.1%

Drug

Topical adapalene is a retinoid that helps in epidermal changes. Cryotherapy is a liquid nitrogen applied to affected parts for 6 months

Topical Liquid Nitrogen application

Procedure

Liquid Nitrogen will be applied to affected parts.

Primary outcomes

  1. Efficacy of Treatment

    Time frame: 06 months

    It will be defined through visual inspection by observing the complete clearance of the warts after 8 weeks administration of the treatment in both groups

Study contacts

Contact information is provided by the study sponsor or research team.

Saba Naz, MBBS

CONTACT

[email protected]

+923209600115

Sponsors and collaborators

Lead sponsor

Khyber Teaching Hospital

Other

Registry information

Official study title

Comparison of Efficacy of Topical Adapalene Gel Versus Cryotherapy in Recurrent Plantar Warts

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jun 11, 2025
Registry last updated
Apr 29, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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