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NCT Number: NCT06978361

Comparison of Efficacy of Microneedling With Platelet Rich Plasma Vs Microneedling With Topical Insulin in the Treatment of Acne Scars

This study compares the outcome of two procedures for the treatment of atrophic acne scars.

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Key information

Conditions

Post-acne Atrophic Scars

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Khyber Teaching Hospital

Peshawar, KPK ,Pakistan, 25000, Pakistan

Location status: Recruiting

About this study

Post acne scars develop due to severely inflamed and nodulocystic acne. Numerous methods exist for the treatment of post acne scars including lasers , microneedling and chemical peels etc . This study is to compare the efficacy two procedures.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients confirmed with post-acne atrophic scars . No prior treatment for scars in last 6 months.

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Exclusion criteria

  • Patient with active acne or other skin conditions (e.g eczema , psoriasis). Patients on oral or topical retinoids. Pregnant or lactating Mothers. Patients with recurrent herpes simplex infection. Previous Hx of keloids / hypertrophic scarring. Deranged blood glucose levels. Bleeding disorders

Treatment and study plan

Microneedling with autologous Platelet Rich Plasma

Procedure

Patients in group A will undergo Microneedling with autologous PRP

Microneedling with topical insulin

Procedure

Patients in group B will undergo Microneedling with Topical insulin ( regular).

Primary outcomes

  1. Efficacy of treatment

    Time frame: 6 months

    Efficacy will be determined by using the Goodman and Baron's Scarring Grading System as" Percentage of decrease in acne scar grade" i.e calculated through subtracting post treatment grade from pre treatment grade and then multiplying it with 100 in both treatment groups .

Study contacts

Contact information is provided by the study sponsor or research team.

Soaiba Naeem, MBBS

CONTACT

[email protected]

+923139493991

Sponsors and collaborators

Lead sponsor

Khyber Teaching Hospital

Other

Registry information

Official study title

Comparison of Efficacy of Microneedling With Autologous Platelet-Rich Plasma vs Microneedling With Topical Insulin in the Treatment of Atrophic Acne Scars

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 18, 2025
Registry last updated
May 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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