Skip to main content
OpenTrials
Completed

NCT Number: NCT02561429

Comparison of Difference Histamine Concentration (1, 5 and 10 mg/ml) for Skin Prick Test Positive Control

Skin prick test (SPT) was used for diagnostic test for type 1 hypersensitivity. The efficacy and safety of SPT were proved. The positive control of SPT is histamine.

In Thailand, the most common concentration of histamine for SPT is 10 mg/ml. However, in some practice they use other concentration (1, 2.5 mg/ml).

This study will find the proper concentration of histamine for positive control use in SPT.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Immediate Hypersensitivity Hypersensitivity Hypersensitivity, Immediate Immune System Diseases

Age range

7 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine Siriraj Hospital

Bangkoknoi, Bangkok, 10700, Thailand

About this study

Appropriate concentration of histamine positive control is important in interpretation the result of skin prick test.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Parcitipate person who attented allergy clinic, ENT clinic
  • Legible in Thai language

Exclusion criteria

  • Patient cannot withhold antihistamine drug
  • Pragnancy and lactation mother
  • comorbid disease such as cardiac disease, liver, renal, hypertension and severe asthma

Treatment and study plan

SPT

Procedure

SPT of histamine concentration 1, 5 and 10 mg/ml

Primary outcomes

  1. Mean wheal diameters of SPT of different histamine concentrations.

    Time frame: 1 years

    compare mean wheal diameters of histamine concentration 1,5, and 10 mg/ml

Secondary outcomes

  1. Mean wheal diameters of SPT of local and imported histamine positive concentration

    Time frame: 1 year

    compare mean wheal diameters of imported histamine 1 mg/ml to local histamine

Sponsors and collaborators

Lead sponsor

Mahidol University

Other

Registry information

Official study title

Comparison of Difference Histamine Concentration (1, 5 and 10 mg/ml) for Positive Control of Skin Prick Test

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Sep 28, 2015
Registry last updated
May 3, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.