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OpenTrials
Completed

NCT Number: NCT02325778

Comparison of CTI Ablation Prior to or After LA Ablation for AF

This study is designed to determine if CTI prior to CPVA/PVI/Linear Lesions/Fractionation results in reduced left atrial ablation lesion sets prior to restoration of sinus rhythm in patients with long standing persistent atrial fibrillation in the absence of antiarrhythmic drug therapy compared to CTI after CPVA/PVI/Linear Lesions/Fractionation.

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Key information

Conditions

Atrial Fibrillation Arrhythmias, Cardiac Cardiovascular Diseases Heart Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

NYU Langone Medical Center

New York, 10016, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • continuous/persistent atrial fibrillation

Exclusion criteria

  • age<18
  • congenital heart disease
  • pacemaker or ICD implant
  • previous ablation

Treatment and study plan

CTI ablation Timing

Procedure

The timing of when the CTI ablation is performed. There are no other relevant interventions used in the procedure.

Primary outcomes

  1. Number of Ablation Lines Required to Organize Atrial Fibrillation to an Atrial Tachycardia or Sinus Rhythm

    Time frame: Acute (intra procedure)

Secondary outcomes

  1. Early recurrence of atrial arrhythmias

    Time frame: 3 months

    Atrial Fibrillation or Atrial Tachycardia lasting longer than 30 seconds

Sponsors and collaborators

Lead sponsor

NYU Langone Health

Other

Registry information

Official study title

Randomized, Single-blind, Comparative Trial of Two AF Ablation Strategies (CTI Ablation Prior to LA Ablation Versus CTI After LA Ablation) to Eliminate Persistent AF

Important dates

Study start
2010
Primary completion
2016
First posted
Dec 25, 2014
Registry last updated
Aug 8, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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