Comparison of Conventional and Non-Conventional CRF and Their Association With Acute Coronary Syndrome

This research aims to compare conventional and non-conventional cardiovascular risk factors and their association with Acute Coronary Syndrome (ACS). Conventional risk factors such as hypertension, diabetes mellitus, dyslipidemia, smoking, and family history are well-established contributors to ACS. However, emerging non-conventional risk factors-including elevated inflammatory markers , homocysteine levels, lipoprotein(a), psychological stress, and lifestyle factors-are gaining attention for their potential role in cardiovascular events.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Notify Me

Key information

Conditions

Coronary Syndrome Angina Pectoris Angina, Unstable Cardiovascular Diseases Chest Pain Heart Diseases Myocardial Ischemia Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Tertiary care hospital

Peshawar, Khyber Pakhtunkhwa, Pakistan

About this study

The study will involve a cross-sectional analysis of ACS patients, examining the prevalence and impact of both types of risk factors. By assessing their relative contributions, the study aims to enhance understanding of ACS pathogenesis, identify at-risk populations more accurately, and support more comprehensive prevention strategies. The findings may help broaden clinical risk assessment tools and guide personalized interventions to reduce the incidence of ACS.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult patients diagnosed with ACS.
Patients providing informed consent for participation.

Exclusion criteria

Patients with chronic heart diseases unrelated to ACS.
Patients unable to provide consent due to critical illness.

Treatment and study plan

Conventional Risk Factor Assessment

Combination Product

Participants in Group 1 will undergo evaluation for conventional cardiovascular risk factors associated with Acute Coronary Syndrome (ACS

Non-Conventional Risk Factor

Combination Product

Participants in Group 2 will be assessed for non-conventional cardiovascular risk factors associated with Acute Coronary Syndrome (ACS).

Primary outcomes

Structured Smoking Questionnaire

Time frame: 12 Months

A structured smoking questionnaire is a tool used to assess an individual's smoking habits, level of nicotine dependence, and potential motivations for smoking. These questionnaires typically include questions about cigarette consumption, brand preferences, smoking patterns, and the perceived effects of smoking.

nterpretation: Higher scores indicate greater nicotine dependence.

Scores:

0-2: Very low dependence 3-4: Low dependence 5: Moderate dependence 6-7: High dependence 8-10: Very high dependence

Sponsors and collaborators

Lead sponsor

Superior University

Other

Registry information

Official study title

Comparison of Conventional and Non-Conventional Cardiovascular Risk Factors and Their Association With Acute Coronary Syndrome

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2026
First posted: Jul 3, 2025
Registry last updated: Jul 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Active, Not Recruiting