Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07244276

Comparison of Compressed Continuous Suture and Conventional Suture in Pterygium Surgery

To compare the advantages and disadvantages of continuous suture with suture and conventional Suture in primary pterygium surgery for autologous conjunctival graft fixation

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Age range

30 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Tianjin Eye Hospital

Tianjin, Tianjin Municipality, China

Location status: Recruiting

Location contact

yan wang, director

CONTACT

[email protected]

+862227313336

About this study

Pterygium is an abnormal fibrovascular tissue hyperplasia disease that occurs in the conjunctiva. The pterygium tissue can break through the limbus of the corneosclera and grow into the cornea, causing a foreign body sensation in the eyes, astigmatism, decreased vision, and even restricted eye movement. The purpose of surgical treatment for pterygium is not only to remove the diseased tissue, but more importantly, to reduce the recurrence of pterygium after surgery. Pterygium excision combined with simple autologous conjunctival transplantation is currently the most commonly used method for treating pterygium. The recurrence rate after autologous conjunctival epithelial tissue transplantation can be reduced to 5% to 30%.

As heterogenic substances, sutures can irritate the ocular surface, aggravate postoperative inflammatory reactions and conjunctival edema or hemorrhage, delay the repair of corneal wound epithelium, lead to abnormal ocular surface function, intensify postoperative discomfort, and induce hypertrophic granuloma or cysts, etc. Moreover, these adverse reactions can also induce the recurrence of pterygium (0-26%). In addition, the longer the time interval between suture removal, The greater the difficulty of removal, the more likely some of the knots may be completely buried under the conjunctiva. Therefore, in order to alleviate the adverse reactions caused by sutures and further simplify the operation of pterygium excision surgery, many attempts have been made at home and abroad to improve and innovate the method of graft fixation.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of primary pterygium according to diagnostic criteria;
  • The pterygium head invades the cornea by 2-5mm;
  • The patient agrees to the surgical treatment and signs the surgical consent form.

Exclusion criteria

  • History of previous eye surgery;
  • Have active ocular inflammatory lesions;
  • recurrent and pseudopterygium;
  • The patient refuses surgery or is unable to have regular follow-ups

Treatment and study plan

Compression continuous suture with suture crimping

Procedure

Pterygium excision combined with autologous conjunctival transplantation was performed, and the continuous suture method with pressure lines was adopted during the operation

Conventional Suture with suture crimping

Procedure

Pterygium excision combined with autologous conjunctival transplantation was performed, and the traditional suture method was adopted during the operation

Primary outcomes

  1. Duration of surgery

    Time frame: Intraoperative

    The date on which the surgery was performed

  2. Implant stability

    Time frame: Postoperative follow-up was performed 1 day and 1 week after surgery

    Whether the conjunctival graft is loose or detached

  3. Postoperative discomfort

    Time frame: Postoperative follow-up was performed 1 day and 1 week after surgery

    The degree of discomfort after surgery was evaluated using the VAS Pain score Scale

  4. Stitch removal time

    Time frame: Postoperative follow-up was performed 1 week after surgery

    The date when the stitches were removed

Study contacts

Contact information is provided by the study sponsor or research team.

Yan Wang, director

CONTACT

[email protected]

23187165 ext. +86 022

Sponsors and collaborators

Lead sponsor

Tianjin Eye Hospital

Other

Registry information

Official study title

Comparison of Compression Continuous Suture Versus Conventional Suture for Autologous Conjunctival Implant Fixation in Primary Pterygium Surgery: a Randomized Controlled Trial

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Nov 24, 2025
Registry last updated
Nov 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.