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NCT Number: NCT07031856

Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM

The aim of this clinical study is to compare CAD-CAM and 3D restorations in individuals with two hard tissue losses or restorations in their mouths. The main question it aims to answer is: Is there a difference between CAD-CAM and 3D restorations according to FDI criteria? Researchers will compare participants to see if there is a difference between the two restorations according to FDI criteria. In this split-mouth study, participants will be randomized to receive a CAD-CAM partial restoration on one tooth and a 3D partial restoration on the other tooth.

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Key information

Conditions

Dental Caries Dental Restoration, Permanent Stomatognathic Diseases Tooth Demineralization Tooth Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Çukurova Üniversitesi Diş Hekimliği Fakültesi

Adana, Sarıçam, 01250, Turkey (Türkiye)

Location status: Recruiting

Location contact

Yaren Coşğun, Dr.

CONTACT

[email protected]

+90 544 745 8633

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

İncluiding:

-- Patients with periodontally stable and appropriate oral hygiene habits without serious systemic diseases that preclude restoration. - Male and female patients with hard tissue loss in their mouth or with 2 teeth in need of restoration replacement (eligibility for split-mouth design). - People who can comply with the treatment and volunteer for follow-up for 2 years-

Exclusion criteria

Patients with systemic conditions that may affect the study process (e.g. diabetes, autoimmune diseases).

  • Patients with excessive bruxism or parafunctional habits.
  • Pregnant or lactating women.
  • Patients with gum disease or severe bone loss.
  • Patients with a history of allergic reactions.

Treatment and study plan

3D printer partial crown

Other

Comprasion of partial restorations made with 3D printer

Treatment as Usual

Other

Cad-cam printer partial crown

Primary outcomes

  1. Clinical performance of dental restorations evaluated using FDI World Dental Federation criteria

    Time frame: Baseline, six months, 12 months

    Esthetic Properties Color match (shade stability) Surface staining Translucency/opacity Anatomical form preservation Functional Properties Fracture and retention Marginal adaptation (gap formation) Wear resistance Occlusal contact stability Biological Properties (Newly added) Postoperative hypersensitivity (pulp reactions) Secondary caries development Periodontal response (gingival inflammation, bleeding on probing) Tooth integrity (adjacent tooth structure)

Study contacts

Contact information is provided by the study sponsor or research team.

Research Assistant

CONTACT

[email protected]

+90 0544 745 8633

Sponsors and collaborators

Lead sponsor

Cukurova University

Other

Registry information

Official study title

Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM: A Split-Mouth Randomized Clinical Trial

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Jun 22, 2025
Registry last updated
Apr 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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