Comparison of Carotid Peak Systolic Velocity Variation With Aortic Peak Systolic Velocity Variation in Pediatric Non-Cardiac Surgery

The purpose of this study is to evaluate whether carotid Doppler peak systolic velocity can be an easy to measure possible surrogate for echocardiographic measurement of aortic peak systolic velocity variation which is an index of fluid responsiveness in mechanically ventilated children intra-operatively.

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Key information

Conditions

Anesthesia, General Anesthesia, Endotracheal Fluid Responsiveness Mechanical Ventilation

Age range

1 year–12 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Postgraduate Institute of Medical Education & Research

Chandigarh, 160012, India

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients scheduled for mon-cardiac surgeries under general endotracheal anaesthesia in supine position with expected duration more than 1 hour

Exclusion criteria

Known congenital heart disease
Any non-sinus rhythm, arrhythmias
Patients on vasoactive medications
Chest wall deformities, situs non solitus (eg. dextrocardia)
Patients scheduled for open chest surgeries
History of neck surgery/ carotid interventions

Treatment and study plan

Measurement of aortic and carotid Doppler peak systolic velocity variation

Other

Aortic peak systolic velocity variation to be measured by echocardiography from apical five chamber and suprasternal windows alongwith carotid peak systolic velocity variation by Doppler ultrasound simultaneously at intermittent time points intermittently.

Primary outcomes

Comparison of carotid peak systolic velocity variation with aortic peak systolic velocity variation

Time frame: Measurements made within 3 minutes

Comparison of carotid peak systolic velocity variation with aortic peak systolic velocity variation by Bland-Altman analysis

Secondary outcomes

Correlation between aortic peak systolic velocity variation measured from apical and suprasternal windows

Time frame: Measurements made within 3 minutes

Correlation between aortic peak systolic velocity variation measured from apical and suprasternal windows by Bland-Altman analysis

Sponsors and collaborators

Lead sponsor

Post Graduate Institute of Medical Education and Research, Chandigarh

Other

Registry information

Important dates

Study start: 2016
Primary completion: 2017
Study completion: 2017
First posted: May 16, 2017
Registry last updated: Apr 16, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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