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OpenTrials
Completed

NCT Number: NCT04941092

Comparison of ARDS COVID-19 (WHO) vs ARDS Influenza in the ICU

Since the beginning of the SARS CoV 2 pandemia, the SARS CoV 2 was frequently compared with the seasonal influenza virus. However, few studies compared patients presenting acute respiratory distress syndrome (ARDS) induced by these viruses, with results being discordant. Our study means to compare mortality and morbidity of patients hospitalized in an intensive care unit (ICU) with ARDS induced by SARS CoV-2 and seasonal influenza.

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Key information

Conditions

ARDS Acute Lung Injury COVID-19 Acute Respiratory Distress Syndrome Infections Influenza Influenza, Human Lung Diseases Lung Injury Orthomyxoviridae Infections RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHRU Nancy

Nancy, 54000, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients hospitalized in ICU
  • under mechanical ventilation
  • presenting an ARDS according to the Berlin definition
  • induced by either influenza or SARS CoV 2

Exclusion criteria

  • pregnant women
  • mechanical ventilation>48 hours before admission

Treatment and study plan

No intervention

Other

no intervention, retrospective comparison

Primary outcomes

  1. mortality

    Time frame: at 28 days

Secondary outcomes

  1. length of stay in ICU

    Time frame: at 28 days

  2. length of mechanical ventilation

    Time frame: at 28 days

  3. length of vasopressors

    Time frame: at 28 days

  4. length of extrarenal epuration

    Time frame: at 28 days

  5. amount of drugs for sedation

    Time frame: at 28 days

Sponsors and collaborators

Lead sponsor

Central Hospital, Nancy, France

Other

Registry information

Official study title

Clinical Outcomes and Characteristics of Critically Ill Patients With Influenza and COVID-19 Induced ARDS: a Retrospective, Matched Cohort Study

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jun 28, 2021
Registry last updated
Jul 12, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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