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NCT Number: NCT06681571

Comparison of Analgesic Effects of TAP Block and RSB in RALPs

In this research, we aim to compare the postoperative analgesic efficacy of these two peripheral blocks in patients undergoing RALP who have received preoperative TAP block and RSB block.

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Key information

Age range

18 year–79 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Zeynep Koç

Yenimahalle, Ankara, Turkey (Türkiye)

About this study

"Robotic-assisted laparoscopic prostatectomy (RALP) is a minimally invasive and superior technique that provides better visualization and maneuverability compared to open and laparoscopic surgical techniques. Previous studies have shown that RALP offers better postoperative oncological and physiological outcomes compared to open and laparoscopic techniques. However, RALP patients still experience pain lasting for several days postoperatively, which requires the use of analgesics such as opioids. This pain is associated with port site incisions, dissection of the prostate and surrounding tissues, bladder spasms, and transurethral catheter irritation. For this purpose, previous studies have utilized central and peripheral methods to reduce postoperative pain. Previous studies have demonstrated the analgesic benefits of TAP block and rectus sheath block in robotic-assisted radical prostatectomies. However, the number of studies in this area is limited. In this research, we aim to compare the postoperative analgesic efficacy of these two peripheral blocks in patients undergoing RALP who have received preoperative TAP block and RSB block.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18-79 who underwent robotic radical prostatectomy
  • Patients have ASA (American Society of Anesthesiologists) physical status score of 1-3.

Exclusion criteria

  • Patients with an allergy to local anesthetic agents
  • a platelet count below 100,000
  • INR value above 2

Treatment and study plan

TAP Block

Other

TAP block will be performed immediately after the induction of anesthesia, under ultrasond guidence.

RSB

Other

Rectus Sheath block will be performed immediately after the induction of anesthesia, under Ultrasond guidence.

Primary outcomes

  1. post operatif analgesia consumption

    Time frame: postoperative 24 hous

    postoperative iv-PCA tramadole dose for the first 24 hours from iv-PCA devices.

Secondary outcomes

  1. numerical rating scale (NRS) at rest

    Time frame: popstoperative 1. hour

    Recording the patient's pain at rest on the Numerical Rating Scale (NRS) by asking the patient

  2. numerical rating scale (NRS) at rest

    Time frame: postoperative 6. hour

    Recording the patient's pain at rest on the Numerical Rating Scale (NRS) by asking the patient

  3. numerical rating scale (NRS) at rest

    Time frame: postoperative 16. hour

    Recording the patient's pain at rest on the Numerical Rating Scale (NRS) by asking the patient

  4. numerical rating scale (NRS) at rest

    Time frame: postoperative 24. hour

    Recording the patient's pain at rest on the Numerical Rating Scale (NRS) by asking the patient

  5. NRS during coughing

    Time frame: postoperative1. hour

    The NRS for pain during coughing will be recorded by asking the patient

  6. NRS during coughing

    Time frame: postoperative 6. hour

    The NRS for pain during coughing will be recorded by asking the patient

  7. NRS during coughing

    Time frame: postoperative 16. hour

    The NRS for pain during coughing will be recorded by asking the patient

  8. NRS during coughing

    Time frame: postoperative24. hour

    The NRS for pain during coughing will be recorded by asking the patient

  9. postoperative nosia and vomiting (PONV)

    Time frame: postoperative 24 hours

    Recording the presence or absence of nausea and vomiting in the patient within the first 24 hours postoperatively

Study contacts

Contact information is provided by the study sponsor or research team.

Zeynep Koc

CONTACT

[email protected]

+905345958843

Sponsors and collaborators

Lead sponsor

Diskapi Yildirim Beyazit Education and Research Hospital

Other Gov

Registry information

Official study title

Comparison of Analgesic Effects of Subcostal Transversus Abdominis Plane Block and Rectus Sheath Block in Robotic-Assisted Laparoscopic Prostatectomies

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Nov 8, 2024
Registry last updated
Nov 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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