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NCT Number: NCT06976424

Comparison of a Face Cream Plus a Laser Procedure and Face Cream Alone in Treatment of Excessive Face Hairs in Female

The study compares the effects of a cream alone and a combined effect of cream and laser for the treatment of excessive facial hairs in women .

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Key information

Conditions

Hirsuitism Hair Diseases Hirsutism Pathological Conditions, Signs and Symptoms Signs and Symptoms Skin Diseases Skin and Connective Tissue Diseases Virilism

Age range

18 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 4

Primary location

Khyber Teaching Hospital, Peshawar, KPK, Pakistan

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About this study

Hirsuitism refers to excessive terminal hairs in females, following a distribution pattern typically associated with male. It is associated with either increase response of hair follicles to androgen or either increase level of circulating androgens.The treatment options available are topical creams like eflornithine and laser treatments for hair removal. This study aims to conduct the comparison of a eflornithine cream and intense pulsed light laser versus eflornithine cream alone for the treatment of excessive facial hairs.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Gender (Female) Age between 18-45 Years Women with hirsutism as mentioned in the operational definition

Exclusion criteria

Pregnant women Women with severe acne Women with immunodeficiency

Treatment and study plan

Eflornithine Topical

Drug

Eflornithine cream will be applied to the face of group B female patients

Other names: Eflornithine cream

Instense pulsed light

Radiation

Intense pulse light will be applied to the face of patient of Group A on areas having increase hair. Patient will be called for a followup every month for next session.

Primary outcomes

  1. Efficacy of treatment

    Time frame: 3 months

    Efficacy of treatment is defined as complete clearance of excessive hairs assesed on the basis of 4- level scale ranging 0 to 3 after 3 months of administration of the treatment in both groups.

    Clear is grade 3 Marked improvement is grade2 Improved is grade1 No improvement is grade 0

Study contacts

Contact information is provided by the study sponsor or research team.

Umaima Nazar, MBBS

CONTACT

[email protected]

+923355869079 ext. +923355869079

Sponsors and collaborators

Lead sponsor

Khyber Teaching Hospital

Other

Registry information

Official study title

Comparison of Eflornithine Cream Combined With Intense Pulsed Light Versus Intense Pulsed Light Alone for Hirsutism in Women

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 16, 2025
Registry last updated
Jul 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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