Ain Shams University Hospitals
Cairo, Egypt
Location status: Recruiting
NCT Number: NCT07517809
The aim of the study is to compare the onset time of the costoclavicular approach of brachial plexus block with that of the lateral-sagittal infraclavicular approach in adults distal upper limb surgeries.
Interested in participating?
Request Info21 year–65 year
All sexes
Interventional
Not applicable
Cairo, Egypt
Location status: Recruiting
Regional anesthesia is commonly used for distal upper limb surgeries as it provides effective surgical anesthesia, reduces opioid consumption, and offers prolonged postoperative analgesia. Ultrasound-guided infraclavicular brachial plexus block is a well-established technique for these procedures. The traditional lateral-sagittal infraclavicular approach (LS-ICB) provides reliable anesthesia but may require multiple needle redirections to achieve adequate spread of local anesthetic around the cords of the brachial plexus. The costoclavicular (CC) approach is a newer ultrasound-guided infraclavicular technique in which the three cords of the brachial plexus are clustered together in the costoclavicular space, potentially allowing easier needle placement and faster spread of local anesthetic.
This prospective randomized controlled trial will include 50 adult patients undergoing distal upper limb surgery under regional anesthesia. Participants will be randomly assigned into two equal groups (25 patients each). Group CC will receive an ultrasound-guided costoclavicular brachial plexus block, while Group ICB will receive an ultrasound-guided lateral-sagittal infraclavicular brachial plexus block.
In both groups, the block will be performed using a mixture of 2% lidocaine and 0.5% bupivacaine in a 1:1 ratio with a total volume of 0.3 mL/kg, administered under real-time ultrasound guidance.
The primary outcome of the study is the time to onset of complete sensory and motor blockade after injection of the local anesthetic solution. Sensory block will be assessed using pinprick testing in the distributions of the median, ulnar, radial, and musculocutaneous nerves.
Secondary outcomes include block performance time, block success rate, incidence of complications (such as vascular puncture, pneumothorax, or local anesthetic systemic toxicity), postoperative pain scores, and total analgesic consumption during the first 24 hours after surgery. The findings of this study may help identify the most effective and safe infraclavicular block technique for distal upper limb surgeries.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Ultrasound-guided costoclavicular brachial plexus block performed using a high-frequency linear probe. A mixture of 2% lidocaine and 0.5% bupivacaine (1:1 ratio) with a total volume of 0.3 mL/kg is injected in the costoclavicular space around the cords of the brachial plexus under real-time ultrasound guidance.
Ultrasound-guided lateral-sagittal infraclavicular brachial plexus block performed using a high-frequency linear probe. A mixture of 2% lidocaine and 0.5% bupivacaine (1:1 ratio) with a total volume of 0.3 mL/kg is injected around the cords of the brachial plexus under real-time ultrasound guidance.
Time frame: From completion of injection up to 30 minutes after block performance
Time from completion of local anesthetic injection to achievement of complete sensory and motor blockade. Sensory block will be assessed using pinprick testing in the distributions of the median, ulnar, radial, and musculocutaneous nerves. Motor block will be graded using a standardized motor scale. And time will be in minutes and seconds.
Contact information is provided by the study sponsor or research team.
Ain Shams University
Other
Comparison Between Ultrasound-Guided Costoclavicular and Lateral-Sagittal Infraclavicular Brachial Plexus Blocks in Adult Distal Upper Limb Surgeries : A Randomized Controlled Trial
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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