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NCT Number: NCT07256145

Comparison Between the Efficacy of Ultrasound-guided Erector Spinae Plane Block and Conventional Treatment for Pain Management in Patients With Post-herpetic Neuralgia

The present study aims to evaluate the efficacy of ultrasound-guided erector spinae plane block with steroids to relieve pain in cases of post-herpetic neuralgia, patient satisfaction, and record any complications post-injection.

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Key information

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Alexandria University

Alexandria, Aleexandria, 21523, Egypt

Location status: Recruiting

Location contact

yasmine ragab elsayed, MD

CONTACT

[email protected]

00201001972418

About this study

The current study will be conducted as a single-blinded prospective randomized controlled study to evaluate the efficacy of ultrasound-guided erector spinae plane block with steroids to relieve pain in cases of post-herpetic neuralgia.

All patients will be evaluated by:

  • Full history taking: including age, sex, presence of co-morbid conditions as well as the presenting complaint.
  • Clinical examination and routine lab investigations that include:
  • Complete blood count (CBC).
  • Fasting blood glucose (FBG).
  • Coagulation profile (bleeding time, prothrombin time, prothrombin activity, international normalized ratio).

Measurements:

Patients will be followed up at 24 hours, 1 week, and 6 weeks after injection.

The following measurements will be recorded:

  • Pain will be assessed pre- and post-injection using VAS score at 24 hours, 1 week, and 6 weeks post-injection.
  • Need for analgesic intake post-injection will be assessed at the follow-up periods.
  • Patient satisfaction using the SAPS score.
  • Complications post-injection as pain, irritation or infection will be assessed.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with post-herpetic neuralgia not responding to medical treatment.

Exclusion criteria

  • 1- Patient refusal 2- Age less than 20 years or older than 70 years. 3- Systemic Infection. 4-Patients with dementia or other diseases that could have impaired their memory or cognitive function.

5- Immunocompromised patients, severe osteoporosis, and uncontrolled diabetes mellitus.

Treatment and study plan

Erector Spinae Plane Block

Procedure

erector spinae plane block with steroids

Primary outcomes

  1. Evaluate the efficacy of ultrasound-guided erector spinae plane block with steroids to relieve pain in cases of post-herpetic neuralgia

    Time frame: 6 weeks

    by VAS score

Secondary outcomes

  1. Patient satisfaction

    Time frame: 6 weeks

    SAPS score

  2. Complications

    Time frame: 6 weeks

    As pain, irritation or infection

Sponsors and collaborators

Lead sponsor

Alexandria University

Other

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 1, 2025
Registry last updated
Dec 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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