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NCT Number: NCT07287579

Comparison Between Platelet Rich Plasma and Nanofat as an Adjuvant Therapy in HairTransplantation

* To compare the efficacy of platlet rich plasma and Nanofat injection as adjuvant therapies with FUE hair transplantation in improving graft survival rate, * To measure hair density and thickness postoperatively using dermoscopy or trichoscopy. * To evaluate patient satisfaction and photographic assessment by blinded evaluators. * To assess any adverse effects or complications related to each modality

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Key information

About this study

  • Ideal candidates for hair transplantation typically present with a clear, stable pattern of hair loss, characterized by at least 50% thinning or balding in 1 or more areas. The scalp must be healthy, with donor hair of good quality and quantity. Patients must have realistic expectations and be free of medical conditions that compromise surgical outcomes. The safe donor zone is located in the mid-occipital region between the upper and lower occipital protuberances, typically containing 65 to 85 follicular units/cm²
  • Intra-operative injection of PRP is beneficial in giving faster density, reducing the catagen loss of transplanted hair, early recovery of the skin, the faster appearance of new anagen hair in FUE hair transplantation.
  • This study compares the effects of PRP and Nano fat as adjuvants in Androgenic alopecia patients undergoing FUE hair transplantation.
  • Nanofat contain stem cells supposed to improve the results of FUE hair transplantation , but the question that we hope to answer at the end of our study which one we recommend as an adjuvant therapy PRP or Nano fat?

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1. Male patients with stable androgenic alopecia more than 2 years. 2. Age 20-50 years 3. No recent medical hair loss treatments.

Exclusion criteria

  • 1. Active scalp infections or scarring alopecia. 2. Systemic diseases affecting wound healing. 3. Platelet disorders or anticoagulant use. 4. Smoking or heavy alcohol intake

Treatment and study plan

Hair transplantation

Procedure

we compare the effect of nanofat injection and platelet rich plasma in hair transplantation in male androgenic alopecia

Other names: hair transplantation with platelet rich plasma, hair transplantation with nanofat injection

Primary outcomes

  1. • To measure hair density using dermoscopy.

    Time frame: • All patients will be followed up about 6-12 months postoperative.

    To measure how many hair follicles in each cubic centimetre

Study contacts

Contact information is provided by the study sponsor or research team.

mostafa haredy, MD

CONTACT

[email protected]

0201095159392

shenouda Faiez, AL

CONTACT

[email protected]

0201285122844

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Comparison Between Platelet Rich Plasma and Nanofat as an Adjuvant Therapy in Hair Transplantation in Male Androgenic Alopecia

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Dec 17, 2025
Registry last updated
Dec 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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