Skip to main content
OpenTrials
Completed

NCT Number: NCT06345092

Comparison Between IPRF With Vit. C and IPRF Alone in Management of ID'Pain

Randomized clinical trial between 2groups,the study group to be injected in the TMJ with injectable platelet rich fibrin with vitamin C and the control group to be injected in the TMJ with injectable platelet rich fibrin alone in management of internal Temporomandibular joint derangement

Completed

Looking for future studies?

Notify Me

Key information

Conditions

TMJ Pain

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Dentistry cairo university

Cairo, +2, Egypt

About this study

Randomized clinical trial between 2groups,the study group to be injected in the TMJ with injectable platelet rich fibrin with vitamin C and the control group to be injected in the TMJ with injectable platelet rich fibrin alone in management of internal Temporomandibular joint derangement

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with internal TMJ derangement (anterior disc displacement with reduction)

Exclusion criteria

Pathological conditions ; trauma TMJ cases or any blood diseases

Treatment and study plan

Vitamin C

Drug

addition of vitamin C to IPRF

Other names: Ascorbic acid

Injectable Platelet Rich Fibrin

Other

injection of IPRF alone

Other names: IPRF

Primary outcomes

  1. Pain management

    Time frame: at 4;8;12;16 weeks

    Evaluation of pain using VAS pre and post injections

Secondary outcomes

  1. disc position using MRI

    Time frame: at 4;8;12;16 weeks

    evaluation of disc position pre and post injections

Other outcomes

  1. maximum mouth opening

    Time frame: at 4;8;12;16 weeks

    measurement of MMO using digital caliper pre and post injections

  2. lateral excursion

    Time frame: at 4;8;12;16 weeks

    measurement of lateral excursion using digital caliper pre and post injections

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Comparison Between Injectable Platelet Rich Fibrin With Vitamin C and Injectable Platelet Rich Fibrin Alone in Management of ID'Pain

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Apr 3, 2024
Registry last updated
Nov 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.