A proforma will be prepared by the researcher and finalized after pre-testing. The patients admitted to Sahiwal Teaching Hospital, Sahiwal will be assessed by the researcher, and the results will be recorded on the proforma. Patients will be admitted to the hospital one day before surgery.
A detailed history of urinary symptoms, sexual function, catheterization, instrumentation, urinary tract infection, and trauma will be obtained to determine the cause of the stricture. Demographic information, including name, age, and contact number, will be recorded. Preoperative investigations will include complete blood count, renal function test, liver function test, urine complete examination, ultrasonography of the kidneys, ureters, and bladder with post-void residual volume (PVR), uroflowmetry, and retrograde urethrogram for the diagnosis and measurement of stricture length.
A midline perineal incision will be made in the lithotomy position from the perineoscrotal junction to about 1 cm from the anal margin. The incision will be deepened through the subcutaneous tissue and Colles' fascia to expose the bulbospongiosus muscle. The bulbospongiosus muscle will be divided in the midline and retracted.
In Group A (excision and primary anastomosis urethroplasty) patients, an incision will be made down onto the catheter in the ventral midline. The urethra will be divided with scissors proximally and distally until healthy urethra is reached. Stay sutures will be placed. The scarred urethra will be excised, and the healthy proximal urethral segment will be spatulated dorsally so that it accommodates a 30 French bougie. The distal urethra will then be spatulated ventrally. The anastomosis will be performed using interrupted 4-0 polydioxanone (PDS) sutures.
In Group B (tunica vaginalis graft urethroplasty) patients, an incision will be made onto the urethra in the ventral midline along the length of the stricture, extending into the healthy proximal and distal urethra, and stay sutures will be positioned. The tunica vaginalis graft will be harvested by making a small vertical or transverse hemiscrotal incision. The dartos fascia will be divided to expose the tunica vaginalis. The testis will be gently delivered through the incision. The graft will be outlined on the parietal tunica vaginalis and carefully dissected while avoiding injury to the testis or epididymis. Hemostasis will be secured. The harvested tunica vaginalis graft will be placed on a sterile surface with the serosal surface facing upward and trimmed to the required size. The graft will be kept moist in normal saline until applied to the urethral site. The tunica vaginalis defect will be approximated, and the testis will be returned to the scrotum. The dartos fascia and skin will be closed in layers using absorbable sutures. The graft will be laid as a ventral onlay graft onto the opened urethral defect and sutured to the urethral mucosal edges using absorbable sutures. Quilting or anchoring sutures may be placed to reduce graft dead space and enhance graft take. The ventral urethrotomy will be closed over the catheter using absorbable sutures.
A 16 French soft silicone catheter will be kept in place for 2-3 weeks for urinary drainage. The bulbospongiosus muscle will be closed in the midline using interrupted 3-0 Vicryl sutures. A suction drain will be placed in the perineum overlying the muscle, and Colles' fascia will be closed using running 3-0 Vicryl sutures, followed by skin closure with running 4-0 chromic sutures. A clear adhesive dressing will be applied, and the patient will be placed in the supine position. The per-urethral Foley catheter will be removed 2-3 weeks after the procedure.
All procedures will be performed by experienced urologists using standardized surgical techniques to ensure consistency. Postoperative follow-up will be conducted at scheduled intervals as specified in the prescribed proforma. Data will be collected using the proforma.
