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OpenTrials
Completed

NCT Number: NCT05265143

Comparision of Two Different Feeding Method in Preterms

achievement of optimal postnatal growth by adequate enteral nutrition in critically ill preterm infants is a challenge of NICU. signs like abdominal distension, reflux, vomiting, nec is a factors of discontinuing fedding in preterm. this factors plays a role in decisions about which method of gavage feeding is adopted. we compare two different feeding method to achive less fedding tolerence.

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Key information

Conditions

Enteral Feeding Intolerance Female Urogenital Diseases and Pregnancy Complications Obstetric Labor Complications Obstetric Labor, Premature Pregnancy Complications Premature Birth Urogenital Diseases

Age range

1 day–3 day

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ümraniye Teaching Hospital

Istanbul, Turkey (Türkiye)

About this study

<1750 gr, <33 gw infants will enroll study. exckusion criteria: major congenital anomalies major gis anomalies

The study infants are enrolled within 24 hours of birth and sequently randomized to either intermitten feeding (IF) and bolus feeding (BF). Intermittent feeding is defined as delivering enteral nutrition and generally giving 60 min and 2 hours no feeding. this circle repeats 8 times in 24 hours. Bolus feeding is the amount of nutrition put into the syringe was kept 10 cm above the baby and the fluidity was obtained by gravity through the orogastric tube. The data of the patients such as feeding intolerance (gastric residual volume more than %50 of the previous feeding volume, gastric regurgitation, abdominal distension and/or emesis ), whether there is a week-by-week feeding intolerance were noted, NEC, time to reached birth weight, time to achieved full enteral feeding, every 5 minutes during feeding, saturation, respiratory rate and heart rates will record.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • <1750 gr preterm infants
  • <33 gw
  • admitted to our nicu in first day of life

Exclusion criteria

major congenital anomalies gis anomalies septic shock exitus in 3 days of life

-

Treatment and study plan

bolus/intermittant feeding

Other

sequential randomization

Primary outcomes

  1. rate of feeding intolerence

    Time frame: 1 month

    The effect of two different gavage tube feeding methods on feeding intolerance

Secondary outcomes

  1. time to reach full enteral feeding

    Time frame: 1 month

    The effect of two different gavage tube feeding methods on time to reach full enteral feeding

Sponsors and collaborators

Lead sponsor

Zekai Tahir Burak Women's Health Research and Education Hospital

Other

Registry information

Official study title

Comparision of Two Different Feeding Method in Preterm Infants

Important dates

Study start
2015
Primary completion
2022
Study completion
2022
First posted
Mar 3, 2022
Registry last updated
Mar 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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