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Completed

NCT Number: NCT06213116

Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray

Comparing the efficacy between Lignocaine given via MADgic Atomizer and Lignocaine Pump Spray pre endotracheal intubation in adult undergoing General Anesthesia.

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Key information

Conditions

Sore Throat Cough Hemodynamic Instability Hoarseness Infections Laryngeal Diseases Nervous System Diseases Neurologic Manifestations Otorhinolaryngologic Diseases Pathological Conditions, Signs and Symptoms Pharyngeal Diseases Pharyngitis Respiration Disorders Respiratory Tract Diseases Respiratory Tract Infections Signs and Symptoms Signs and Symptoms, Respiratory Stomatognathic Diseases Voice Disorders

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Science Malaysia Hospital

Kubang Kerian, Kelantan, 16150, Malaysia

About this study

Comparing the efficacy of Lignocaine given via 2 device (Lignocaine Spray and MADGIC Atomizer) on hemodinamic parameters postintubations and severity grading of post operative sore throat, cough and hoarseness of voice.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult with the age of 18 to 65 years old
  • Gender of both male and female
  • Planned for elective surgery scheduled at General Operation Theatre that require elective intubation for general anesthesia
  • American Society Anaesthesiologist (ASA) preoperative physical status assessment of 1 and 2
  • Airway assessment Malampati scoring 1and 2.

Exclusion criteria

  • Pregnancy
  • Known allergy or hypersensitivity to Lignocaine
  • Pre existing sore throat or hoarseness of voice identified during preoperative assessment.
  • The use of airway device other than endotracheal tube (ETT) such Laryngeal Mask airway/Supraglottic Device'
  • Oral and neck surgery

Treatment and study plan

MADgic Atomizer

Device

Device to deliver directly lignocaine

Lignocaine pump spray

Device

Lignocaine 30 mg (3 puffs) given via 10mg Lignocaine Pump Spray prior to endotracheal intubation

Primary outcomes

  1. Severity Grading of Post Operative Sore Throat

    Time frame: 24 hours

    Numbers of participants complaining incidence of sore throat postoperatively

Secondary outcomes

  1. Severity Grading of Post Operative Cough

    Time frame: 24 hours

    Numbers of participants complaining incidence of cough postoperatively

  2. Severity grading of Hoarseness of voice

    Time frame: 24 hours

    Numbers of participants complaining incidence of hoarseness of voice postoperatively

Sponsors and collaborators

Lead sponsor

Universiti Sains Malaysia

Other

Registry information

Official study title

Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray Pre Endotracheal Intubation in Adult Undergoing General Anesthesia.

Important dates

Study start
2021
Primary completion
2023
Study completion
2023
First posted
Jan 19, 2024
Registry last updated
May 21, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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