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OpenTrials
Active, Not Recruiting

NCT Number: NCT06128239

Comparing Suicide Prevention Interventions to Guide Follow-up Care: The SPRING Trial

Pragmatic randomized controlled trial to compare the effectiveness of two-way Caring Contacts text messages vs. one-way Caring Contacts text messages vs. enhanced usual care for suicide prevention in adults and adolescents.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

12 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

St. Luke's Health System

Boise, Idaho, 83712, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adolescents (12-17 years old) and adults (18+)
  • Response of "yes" to at least one item on the Columbia Suicide Severity Rating Scale (C-SSRS) six-item screener at a St. Luke's Health System (SLHS) primary care or behavioral health clinic, or electronic health record or provider note from an eligible encounter indicates suicide risk
  • Ability to send and receive text messages
  • Ability to receive phone calls
  • Ability to receive emails
  • Participant and legal guardian (if applicable) speak, read, and understand English
  • Accommodations may be made for individuals with impaired hearing

Exclusion criteria

  • Individuals who participated in a previous randomized controlled trial in the same health system related to Caring Contacts (SPARC Trial or MHAPPS Trial)
  • Patients who are unable or unwilling to provide informed consent*, for example, due to acute or chronic cognitive impairment (i.e.: acute psychosis, intoxication, or intellectual disability).
  • Primary Care Provider, Behavioral Health Provider, or Principal Investigator determines that participation in the research is not in the best interest of the patient or the study team.

Treatment and study plan

Caring Contacts

Behavioral

Text message version of Motto's Caring Contacts intervention. The study will compare two versions of text-based Caring Contacts: two-way messages, to which participants can respond to receive text-based support from follow-up specialists, and one-way text messages, to which participants cannot respond.

Other names: Caring Texts, Caring Letters

Primary outcomes

  1. Suicidal behavior

    Time frame: Baseline, 3 months, 6 months, 12 months

    Measured using the Harkavy-Asnis Suicide Scale (HASS) Active Suicidal Behavior Sub-Scale. The HASS has been validated for self-report, with strong psychometric properties in adolescents and adults. This measure asks about the frequency of suicide attempt planning, and actual and aborted/interrupted suicide attempts. Participants respond using the Likert scale response options used by Asarnow et al.'s validation study, modified to fit the survey time period (past six months at baseline/12-month outcome surveys, and past 3 months for 3- and 6-month outcome surveys). Each HASS sub-scale is scored separately by summing the response values. Scores on the Active Suicidal Behavior Sub-Scale range from 0 - 20, with higher scores corresponding to higher suicide risk. The primary outcome will be the cumulative risk of suicidal behavior assessed using area under the curve of the HASS scores over the 12-month study period.

Secondary outcomes

  1. Suicide attempts

    Time frame: Baseline, 3 months, 6 months, 12 months

    Suicide attempts will be measured using the Columbia Suicide Severity Rating Scale (C-SSRS), which is valid for adolescents and adults.

  2. Suicide ideation

    Time frame: Baseline, 3 months, 6 months, 12 months

    Suicidal ideation will be measured using the Passive Suicidal Ideation Subscale of the Harkavy-Asnis Suicide Scale (HASS), which includes 12 items. Scores on the Passive Suicidal Ideation Sub-Scale range from 0 - 48, with higher scores corresponding to higher suicide risk.

  3. Suicide-related Emergency Department (ED) utilization and hospitalization

    Time frame: Baseline, 3 months, 6 months, 12 months

    Suicide-related ED utilization and hospitalization will be assessed by self-report and using electronic medical records. Reason for visit/diagnoses may be reviewed in electronic medical records for any inpatient or outpatient encounters that occur during the study period.

  4. Outpatient mental health treatment

    Time frame: Baseline, 3 months, 6 months, 12 months

    Outpatient mental health treatment will be self-reported and assessed using electronic medical records. Reason for visit/diagnoses may be reviewed in electronic medical records for any inpatient or outpatient encounters that occur during the study period.

Other outcomes

  1. Thwarted belongingness

    Time frame: Baseline, 3 months, 6 months, 12 months

    Thwarted belongingness will be measured using the 15-item version of the Interpersonal Needs Questionnaire.

    The 15-item version of the Interpersonal Needs Questionnaire (INQ15) is a validated tool to measure both perceived burdensomeness (PB) (6 items, scores range from 6 to 42) and thwarted belongingness (TB) (9 items; scores range from 9 to 63), which are related to desire for suicide. Individuals provide a self-report response to each of 15 items using a Likert scale ranging from 1 (Not at all true for me) to 7 (Very true for me). The appropriate items are reverse coded, and items are summed to calculate the TB and PB subscale scores with higher scores indicating greater TB and PB. Clinical Cutoff scores predicting desire for death are 35 or greater for TB and 19 or greater for PB. Clinical cutoff scores predicting desire for suicide are 50 or greater for TB and 30 or greater for PB.

  2. Perceived burdensomeness

    Time frame: Baseline, 3 months, 6 months, 12 months

    Perceived burdensomeness will be measured using the 15-item version of the Interpersonal Needs Questionnaire.

    The 15-item version of the Interpersonal Needs Questionnaire (INQ15) is a validated tool to measure both perceived burdensomeness (PB) (6 items, scores range from 6 to 42) and thwarted belongingness (TB) (9 items; scores range from 9 to 63), which are related to desire for suicide. Individuals provide a self-report response to each of 15 items using a Likert scale ranging from 1 (Not at all true for me) to 7 (Very true for me). The appropriate items are reverse coded, and items are summed to calculate the TB and PB subscale scores with higher scores indicating greater TB and PB. Clinical Cutoff scores predicting desire for death are 35 or greater for TB and 19 or greater for PB. Clinical cutoff scores predicting desire for suicide are 50 or greater for TB and 30 or greater for PB.

  3. Suicidal ideation & behavior

    Time frame: Baseline, 3 months, 6 months, 12 months

    A combined indicator of suicidal ideation and behavior will be assessed using the Columbia Suicide Severity Rating Scale self-report 6-item screener for primary care (C-SSRS) plus several additional items from the full Columbia Suicide Severity Rating Scale (interview) (interrupted suicide attempts, self-aborted suicide attempts, actual suicide attempts, and suicide deaths). Scores range from 0 (no suicide risk indicated) to 10 (death by suicide), with higher scores indicating higher suicide risk.

  4. Suicide attempts (including actual, aborted, or interrupted attempts)

    Time frame: Baseline, 3 months, 6 months, 12 months

    The frequency of suicide attempts (including actual attempts, interrupted attempts, and self-aborted attempts) will be measured using the two-item Suicide Attempts Sub-Scale of the Harkavy-Asnis Suicide Scale (HASS). Scores on the Suicide Attempts Sub-Scale range from 0 - 8, with higher scores corresponding to higher suicide risk.

  5. Perceived mattering to others

    Time frame: Baseline, 3 months, 6 months, 12 months

    The General Mattering Scale (GMS) will be used to assess the extent to which participants believe they matter to other people. Participants use a Likert scale from 1-4 to respond to each of five items. Scoring is completed by summing the responses, with results ranging from 5 to 20 and higher scores corresponding to higher levels of perceived mattering to others (better outcomes).

  6. Non-suicidal self-injury

    Time frame: Baseline, 3 months, 6 months, 12 months

    Non-suicidal self-injury will be measured with select items from the Self-Injurious Thoughts and Behavior Interview - Revised (SITBI-R). Each item is assessed individually, and items are not scored together in a scale.

  7. All-cause ED utilization and hospitalizations

    Time frame: Baseline, 3 months, 6 months, 12 months

    The number of and reason for visit/diagnoses for ED encounters and hospitalizations will be assessed using electronic medical records.

  8. Completed suicide

    Time frame: Baseline, 3 months, 6 months, 12 months

    The manner and cause/lethal means of all deaths including death by suicide will be assessed based on electronic medical records and vital records

  9. All-cause mortality

    Time frame: Baseline, 3 months, 6 months, 12 months

    The manner and cause/lethal means of all deaths including death by suicide will be assessed based on electronic medical records and vital records

  10. Suicide Attempts

    Time frame: Baseline, 3 months, 6 months, 12 months

    Suicide attempts will also be measured with select items from the Self-Injurious Thoughts and Behavior Interview - Revised (SITBI-R). Each item is assessed individually, and items are not scored together in a scale. Some items are dichotomous (e.g.: ever vs never had a suicide attempt). Several items ask for an age or date when suicide attempts occurred. The number of reported suicide attempts ranges from 0+, with no upper limit to the range.

Sponsors and collaborators

Lead sponsor

St. Luke's Health System, Boise, Idaho

Other

Collaborators

  • American Foundation for Suicide Prevention
  • Idaho Crisis & Suicide Hotline
  • University of Washington

Registry information

Official study title

Comparing the Effectiveness of Two-Way Caring Contacts Texts vs One-Way Caring Contacts Texts vs Enhanced Usual Care to Reduce Suicidal Behavior in Youth and Adults Screening At-Risk for Suicide in Primary Care or Behavioral Health Clinics

Acronym: SPRING

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Nov 13, 2023
Registry last updated
Jul 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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