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NCT Number: NCT06899867

Comparing Montiroing Cardiac Index by Transpulmonary Thermodilution and Transesophageal Echocardiography During Liver Transplantation

Liver transplantation poses challenges due to hemodynamic changes throughout different surgical phases. Monitoring devices are essential for therapeutic adjustments. Transpulmonary thermodilution and transesophageal echocardiography are commonly used, but thermodilution may have limitations depending on the surgery.

This study aims to compare cardiac index variations between thermodilution and transesophageal echocardiography during liver transplantation. Patients undergo monitoring with both techniques. Measurements are recorded and reported at multiple time points.

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Key information

Conditions

Liver Transplantation

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Croix Rousse Hsopital

France, Lyon, 69004

Location status: Recruiting

Location contact

BLET Alice, MD,PhD

CONTACT

[email protected]

371239

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • liver transplantation
  • adults

Exclusion criteria

  • - Oesophageal varice ligation < 14 days
  • Mediastinal radiotherapy
  • Femoral bypass
  • Severe lower extremity artery disease

Treatment and study plan

Measure of cardiac index with thermodilution and transesophageal echocardiography

Other

At 4 times of surgery, end-expiratory occlusion (EEO) test and measure of cardiac index before and after test with ETO and thermodilution

Surgical anastomosis echography

Other

Visualisation of surgical anastomosis through transesophageal echocardiography : stenosis, doppler velocity, collar diameter

Primary outcomes

  1. Cardiac index variation measured by thermodilution compared with transesophageal echography

    Time frame: At 4 times of surgery: after starting anesthesia, anhepatic phase, reperfusion and surgical anastomosis of biliary ducts. Data reported : - Cardiac Index before and after end-expiratory test. - Transoesophageal echography measurement of cardiac function

Study contacts

Contact information is provided by the study sponsor or research team.

Pr Alice Blet

CONTACT

[email protected]

371239

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Official study title

Is Cardiac Index, Assessed by Transpulmonary Thermodilution, Reliable During Liver Transplantation Compared to Transesophageal Echocardiography : a Monocentric Cohort

Important dates

Study start
2023
Primary completion
2024
Study completion
2025
First posted
Mar 28, 2025
Registry last updated
Mar 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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