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Completed

NCT Number: NCT01348685

Comparing Liquid Versus Solid Forms of Sugars and Whey Protein

To compare the effect of eating solid vs. drinking liquid forms of gelatin, sucrose and its component mixtures and whey protein on subjective appetite and food intake in young men.

Completed

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Key information

Age range

19 year–28 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University of Toronto, Department of Nutritional Sciences

Toronto, Ontario, M5S 3E2, Canada

About this study

Three randomized cross-over design experiments were used to compare the effect of solid and liquid forms of gelatin (6 g) in experiment 1, sucrose (75 g) and a mixture of 50% glucose/ 50% fructose (G50:F50) in experiment 2, and acid and sweet whey protein (50 g) in experiment 3 on healthy normal weight males . The controls were water (experiment 1 and 3) and calorie-free sweetened water with gelatin (sweet gelatin, experiment 1) or without gelatin (sweet control, experiment 2). Subjective average appetite was measured by visual analogue scales frequently over 1 h and ad libitum food intake was measured 1 h after the treatment consumptions.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy lean males with BMI between 18- 24.9 kg/m2 and an age range of 19 to 28 years were recruited for the three experiments.

Exclusion criteria

  • Diabetics (fasting blood glucose ≥ 7.0 mmol/L), smokers, breakfast skippers or dieters were excluded from the experiments. Individuals under medications or with a history of liver or kidney disease and major medical or surgical event within the last six months were excluded.

Treatment and study plan

Compare the effect of solid vs. liquid forms of sugars on satiety and food intake

Other

the effect of solid vs. liquid forms of gelatin on appetite and food intake

Other

The effect of solid vs. liquid forms of whey protein on food intake

Other

Primary outcomes

  1. subjective appetite and short term food intake

    Time frame: 60 min

Sponsors and collaborators

Lead sponsor

University of Toronto

Other

Collaborators

  • Canadian Sugar Institute
  • Mondelēz International, Inc.
  • Natural Sciences and Engineering Research Council, Canada

Registry information

Official study title

Effect of Drinking Liquid Compared to Eating Solid Treatment of Sugars or Whey Protein on Short-term Appetite and Food Intake

Important dates

Study start
2007
Primary completion
2009
Study completion
2009
First posted
May 5, 2011
Registry last updated
May 5, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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