Thammasat University Hospital
Khlong Luang, Changwat Pathum Thani, 12120, Thailand
NCT Number: NCT05139875
The purpose of this study is to compare the efficacy of Intra-articular corticosteroid injection between Betamethasone (Diprospan) and Triamcinolone acetonide for treatment of knee osteoarthritis
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Interventional
Phase 4
Khlong Luang, Changwat Pathum Thani, 12120, Thailand
After being informed about the study and potential risks, all patients giving written informed consent will be chosen for eligibility for the study entry. At day 0 (before intra-articular injection), patients who meet the eligibility criteria will be randomized in a double-blind manner (participant and investigator) in a 1:1 ratio to Betamethasone (Diprospan 1 ml) or Triamcinolone acetonide (40 mg) single intra-articular injection
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Single intra-articular Betamethasone Dipropionate / Betamethasone Sodium Phosphate (Diprospan) injections to affected knee
Other names: Diprospan
Single intra-articular Triamcinolone Acetonide injections to affected knee
Other names: Kanolone-F
Time frame: Baseline before intra-articular injection, 1 day, 2 days, 3 days, 1 week, 3 weeks, 1 month, 2 months, 3 months, 4 months, 5 months, 6 months after the day of intra-articular injection
Time frame: Baseline before intra-articular injection,1 month, 3 months, 6 months after intra-articular injection
Time frame: Baseline before intra-articular injection,1 month, 3 months, 6 months after intra-articular injection
Time frame: Baseline before intra-articular injection,1 month, 3 months, 6 months after intra-articular injection
Time frame: Baseline before intra-articular injection,1 month, 3 months, 6 months after intra-articular injection
Time frame: Baseline before intra-articular injection,1 month, 3 months, 6 months after intra-articular injection
Time frame: 1 month, 3 months, 6 months after intra-articular injection
Injection site reaction, Erythema, Swelling, Injection-site pain, Pruritus, cellulitis were observed after intra-articular injection.
Time frame: 6 months after intra-articular injection
Thammasat University
Other
A Comparative Study of Betamethasone (Diprospan) and Triamcinolone Acetonide as Single Intra-Articular Injection in Knee Osteoarthritis, A Double-Blinded, Randomized Controlled Trial
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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