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Completed

NCT Number: NCT07569770

Comparing High-Protein and Low-Protein Multi-Ingredient Supplements for Body Composition and Performance in Elite Rugby Players

The purpose of this 12-week study is to compare the effects of two different post-exercise nutritional supplements on the body composition and exercise performance of elite male university rugby players. Athletes often consume very high amounts of protein to build muscle and recover, but excessive protein intake might pose potential health risks.

Study Hypothesis:

The researchers hypothesize that a multi-ingredient supplement with a lower total protein content (about 20 grams) will yield comparable or even superior improvements in body composition and physical performance compared to a standard high-dose whey protein supplement (40 grams).

Study Design:

Twenty elite male college rugby players will be randomly divided into two equal groups. One group will receive the high-dose whey protein, while the other group will receive the lower-dose multi-ingredient supplement (which includes protein, leucine, creatine, red amaranth, and elderberry). Participants will consume their assigned supplement immediately after their training sessions, four times a week for 12 weeks.

Assessments:

Before and after the 12-week intervention, the researchers will measure the participants' body composition (muscle and fat mass), maximum muscle strength, power, agility, and aerobic endurance. The overall goal is to determine if athletes can achieve optimal performance and muscle growth with a lower, more efficient protein intake strategy.

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Key information

Age range

19 year–26 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Institute of Sports Sciences, University of Taipei

Taipei, 111036, Taiwan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Elite rugby athletes in the university team
  • No consumption of performance-enhancing supplements (e.g., creatine, protein supplements, or anabolic-androgenic steroids) one month prior to the study
  • No current medication or major musculoskeletal injuries

Exclusion criteria

  • Vegetarianism
  • Whey protein allergy
  • Body weight fluctuation of more than 10 kg in the past three months

Treatment and study plan

Whey Protein Concentrate

Dietary Supplement

Participants consume 40 g of Whey Protein Concentrate (WPC-80), providing 166 kcal, 32 g of protein, 5 g of carbohydrate, and 2 g of fat per serving. It is consumed immediately after training, four times per week for 12 weeks.

Single Formulated Multi-Ingredient Supplement

Dietary Supplement

Participants consume a single, pre-mixed formulated supplement powder containing approximately 20 g of protein (whey protein fortified with additional leucine and glycine), 30 g of carbohydrates, creatine, red amaranth extract, and elderberry extract (169 kcal). It is consumed immediately after training, four times per week for 12 weeks.

Primary outcomes

  1. Change in Muscle Mass

    Time frame: Baseline and Week 12

    Muscle mass is assessed using Dual-energy X-ray Absorptiometry (DXA). The change is evaluated by comparing the baseline values to the post-intervention values.

Sponsors and collaborators

Lead sponsor

University of Taipei

Other

Registry information

Official study title

Comparison of High and Low Protein Dose With Multi-ingredient Supplementation for Body Composition and Exercise Performance in Elite Rugby Players

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
May 6, 2026
Registry last updated
May 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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