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Completed

NCT Number: NCT04738929

Comparing EVCO and EVOO

The aim of this study is to compare acute effects of consuming extra virgin coconut oil (EVCO) as a source of medium chain fatty acids and extra virgin olive oil (EVOO) as a source of long chain fatty acids in normal weight and obese subjects.

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Key information

Conditions

Obesity Appetitive Behavior Behavior Behavior, Animal Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

19 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Presidency of Republic of Turkey Health Center

Ankara, Turkey (Türkiye)

About this study

Twenty male subjects (10 normal weight; 10 obese) consumed breakfast meals containing skimmed milk, fat-free white cheese, bread and EVCO (25 g) or EVOO (25 g). Visual analog scale evaluations, resting metabolic rate measurements and selected blood parameters analysis (glucose, triglyceride, insulin and plasma peptide YY) were performed before and after the test breakfast meals. In addition, energy intakes were evaluated by ad libitum lunch meal at 180 min.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Metabolically healthy
  • Aged 19-40 years
  • Normal weight (BMI=18.5-24.9 kg/m²) and obese men (BMI=30-34.99 kg/m²)

Exclusion criteria

  • smoking,
  • alcohol consumption,
  • weight gain/loss recently (> %5, in three months),
  • any genetic and metabolic diseases,
  • any food allergy/intolerance,
  • any medication,
  • restrained eating habits.

Treatment and study plan

Extra virgin coconut oil or extra virgin olive oil

Other

Subjects consumed standard breakfast meals containing "extra virgin coconut oil" or "extra virgin olive oil"

Primary outcomes

  1. Energy expenditure change

    Time frame: 0, 60, 120, 180 minutes

    kcal

  2. Subjective appetite feelings change

    Time frame: 0, 30, 60, 120, 180 minutes

    visual analogue scales rating (0-10 cm)

  3. glucose change

    Time frame: 0, 30, 60, 120, 180 minutes

    mg/dl

  4. insulin change

    Time frame: 0, 30, 60, 120, 180 minutes

    mU/L

  5. peptide YY change

    Time frame: 0, 30, 60, 120, 180 minutes

    pg/dl

  6. triglycerides change

    Time frame: 0, 30, 60, 120, 180 minutes

    mg/dl

  7. Ad libitum energy intake

    Time frame: 180 minute

    kcal

Sponsors and collaborators

Lead sponsor

Ankara City Hospital Bilkent

Other

Collaborators

  • Hacettepe University

Registry information

Official study title

Comparing Acute Effects of Extra Virgin Coconut Oil and Extra Virgin Olive Oil Consumption on Appetite and Food Intake in Normal Weight and Obese Male Subjects

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Feb 4, 2021
Registry last updated
Feb 4, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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