Ente Ospedaliero Cantonale, Bellinzona
Bellinzona, 6500, Switzerland
NCT Number: NCT05798585
The aim of the study is to compare two different locoregional techniques in VATS.
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Notify MeThere are clear clinical and logistic reasons for pursuing the best possible post-operative pain management avoiding the negative side effects of opioid treatment; in order to garantee an enhanced recovery after surgery. A short hospital stay is fundamental to reduce patient morbidity and costs. Regional anesthetic nerve blocks are an ideal option to achieve this goal.
Paravertebral block serves as an ideal approach for thoracic and abdominal surgery through delivering segmental anesthesia of operative sites. Thoracic paravertebral block has superior analgesia as well as fewer complications than systemic opioids. It has been successfully applied in sternotomy, breast surgery, abdominoplasty, and laparoscopic cholecystectomy. ESP block is a recently described technique, with promising results in different scenarios. It probabily has a better risk profile than PVB, for its lower possibility of accidental pleural puncture and reabsorption of local anesthtetic than PVB one
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
US guided ESP infiltration (saline solution vs Ropivacaine 0.375% according to randomization): unilateral injection of 0,4 ml kg -1 (ideal weight)2 under US guidance between the deep fascia of erector spinae muscle and the two transverse processes at the level of the 5th thoracic vertebrae. Duration approximately 10-15 minutes
Time frame: 48 hours
by using a PCA we will see how many times the patient asked for analgesia
Time frame: 48 hours
we will test pain score in several moment by asking the NRS scale at rest and during cough
Time frame: 48 hours
we will compare the systolic pressure before anesthesia and after the block have been performed
Time frame: 48 hours
we will check if any cardio-pulmonary complication is present after surgery during the hospital stay
Time frame: 48 hours
we will observe the time necessary to perform the block and the complications after it
Time frame: 48 hours
We will observe if the patient need any type of anti-nausea medication
Time frame: 48 hours
We will observe if any episode of vomiting is present
Time frame: 48 hours
We will observe if any episode of urinary retention is present
Time frame: 48 hours
We will observe how long the hospital stay is
Time frame: 48 hours
We will observe if the patient needs for an epidural catheter
Andrea Saporito
Other
Comparing Erector Spinae Plane (ESP) and Thoracic Paravertebral (TPV) Block Analgesic Effect After Elective Video Assisted Thoracic Surgery (VATS): a Single Center, Randomized, Multiple-blinded, Controlled, Non Inferiority Trial
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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