Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07484399

Comparing Effects of HIIT and MICT on Functional Mobility, Muscle Strength, and Quality of Life in Diabetic Patients

To compare the effects of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) on functional mobility, muscle strength, and quality of life in individuals with type-2-diabetes.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Type 2 Diabetes Mellitus With Complication

Age range

35 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Comparing the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on functional mobility, muscle strength, and quality of life in diabetic patients is important due to the increasing burden of diabetes and its associated complications. Diabetes often leads to reduced physical function, muscle weakness, and poor quality of life. While both HIIT and MICT have demonstrated positive effects on health outcomes, it is not yet clear which exercise regimen offers superior benefits for improving mobility, strength, and overall well-being in diabetic individuals.

Diabetes often leads to reduced physical function, muscle weakness, and poor quality of life. While both HIIT and MICT have demonstrated positive effects on health outcomes, it is not yet clear which exercise regimen offers superior benefits for improving mobility, strength, and overall well-being in diabetic individuals. Understanding this can guide the development of more effective exercise protocols for diabetes management.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

:• Adults aging form 35 to 65.

  • Both male and female diabetic patients.
  • Individuals diagnosed with type 2 diabetes for at least five years.
  • Individuals able to participate in moderate to intense physical activity.

Exclusion criteria

  • • Individuals with significant orthopedic limitations.
  • Individuals with uncontrolled cardiovascular disease or musculoskeletal issues.
  • Individuals with incontinence issues during physical activity or inability to comply to study protocols

Treatment and study plan

High Intensity Interval Training

Other

3 session per week, 12 weeks sessions continued, each session had 4 sets of 4 minutes exercise with 3 min active rest inbetween routines. total 30 minutes per session, Sprinting and Jump squatting RPE 15-18

Moderate Intensity Continuous Training

Other

3 session per week, 12 weeks sessions continued, 40 minutes one single exercise regime with no intervals. Brisk Walking on Treadmill, RPE-11-13

Primary outcomes

  1. TUG timed up go test

    Time frame: baseline pre exam, 6th week of intervention, and 12th week

    Functional mobility is evaluated by the TUG test. The TUG test has revealed very high test-retest reliability among patients with diabetes, as shown by the ICC values from 0.93 to 0.99

  2. Hand Grip Strength Test

    Time frame: baseline pre exam, 6th week of intervention, and 12th week

    To assess the power of muscles a dynamometer used to test the gripping power of participants making an objective estimate of the strength of the muscles in the upper body. This method had the same validity as that of the whole functional capacity in diabetic populations, with coefficients of 0.70 to 0.85 being most common

  3. Chair Stand Test

    Time frame: baseline pre exam, 6th week of intervention, and 12th week

    In order to evaluate again the strength of the lower limb muscles. The individuals were measured how fast they could stand up from a chair and sit down again and again, which is an indicator of muscle endurance and functional strength. The test has shown really high reliability in diabetic populations with ICC values being around 0.85 to 0.91.

  4. The Borg 6-20 Scale

    Time frame: baseline pre exam, 6th week of intervention, and 12th week

    The Borg 6-20 scale used to measure the rate of perceived exertion. It has a strong relationship with heart rate and oxygen consumption with the range of correlation coefficients between 0.80 and 0.88 for diabetic individuals. The Borg RPE scale in T2DM has a test-retest reliability indicated by the Intraclass Correlation Coefficient (ICC) of about 0.85 to 0.92, which means that people give similar ratings of their exertion consistently across repeated sessions in similar exercise conditions

  5. WHOQOL-BREF Questionnaire

    Time frame: baseline pre exam, 6th week of intervention, and 12th week

    The WHOQOL-BREF is a universal instrument that measures the quality of life in different aspects such as physical health, psychological health, social relationships, and environment. In patients with diabetes, the WHOQOL-BREF reveals a strong internal consistency with Cronbach's alpha values ranging from 0.76 to 0.88

Study contacts

Contact information is provided by the study sponsor or research team.

Imran Amjad, Phd.

CONTACT

[email protected]

03324390125

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Comparing The Effects of High Intensity Interval Training and Moderate Intensity Continuous Training on Functional Mobility, Muscle Strength, and Quality of Life in Diabetic Patients

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 20, 2026
Registry last updated
Mar 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.