Benisuef university hospital
Benisuef, Egypt
Location status: Recruiting
NCT Number: NCT06612125
The most basic modes of mechanical ventilation are volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV). VCV guarantees a target volume of ventilation using a constant flow, but may lead to high peak airway pressure (Ppeak) during the gas insufflation . In PCV mode, on the other hand,
Interested in participating?
Request Info1 year–5 year
All sexes
Interventional
Not applicable
Benisuef, Egypt
Location status: Recruiting
The laryngeal mask airway (LMA) provides a useful alternative for airway management during general anaesthesia. Inflation of the LMA cuff produces a low-pressure seal around the larynx, enabling positive pressure ventilation (PPV). The use of LMA as an airway management technique is common in the pediatric anesthesia because of its less irritating effect on the airways due to its location in the upper larynx. Now, the use of laryngeal mask instead of tracheal intubation for airway management has been achieved in day surgery, therefore, how to perform a respiratory management with a laryngeal mask is particularly important. In addition, mechanical ventilation is also a commonly used method of airway management in clinical practice. the ventilator will deliver a constant pressure by decelerating the flow. However, the ventilation volume varies according to the patient's respiratory mechanics . Pressure-controlled ventilation-volume guaranteed (PCV-VG) combines the advantages of both VCV and PCV, which delivers a stable ventilation volume using a decelerating flow pattern.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Pediatric patients in the VCV group (n= 30) received volume-controlled ventilation, target tidal volume was set at 7 mL/kg, with a respiratory rate of 16 breaths/min and a respiratory ratio of 1:2.
Pediatric patients in the PCV group(n=30) received pressure-controlled ventilation. The initial parameters will be as follows: the peak inspiratory pressure (PIP) will set to provide a tidal volume of 7 ml/kg , respiratory rate will be 16 breaths/min, inspiratory to expiratory ratio was 1:2 with an upper limit of PIP of 20 cm H2O.
Pediatric patients in the PCV-VG group (n=30)will be conducted with pressure-controlled volume-guaranteed ventilation, target tidal volume will set at 7 mL/kg, with a respiratory rate of 16 breaths/min and a respiratory ratio of 1:2.
Time frame: within one hour
peak inspiratory pressure
Time frame: within one hour
plateau airway pressure
Time frame: within one hour
pulmonary dynamic compliance
Time frame: within one hour
airway resistance
Time frame: within one hour
exhaled tidal volume
Time frame: within one hour
end-expiratory carbon dioxide
Time frame: within one hour
physiologic dead space over tidal volume
Time frame: within one hour
mean arterial pressure
Time frame: within one hour
heart rate
Time frame: within 24 hour
cough, hoarseness, sore throat, hypoxemia, laryngospasm, bronchospasm.
Contact information is provided by the study sponsor or research team.
Beni-Suef University
Other
Comparison of Positive Pressure Ventilation Strategies in Young Children Undergoing Laparoscopic Inguinal Hernia Repair With Laryngeal Mask Airway: A Prospective Randomized Study
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT04498598
Airway Complication of Anesthesia, Hypoventilation
Cleveland, Ohio, United States
View Trial DetailsNCT04068012
ARDS, Acute Lung Injury
Chicago, Illinois, United States
View Trial DetailsNCT04484727
Cross Infection, Disease Attributes
Gothenburg, Västra Götaland County, Sweden
View Trial DetailsNCT06142773
Ventilation Therapy; Complications
Toronto, Ontario, Canada
View Trial Details