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NCT Number: NCT05763810

Comparing Different Regional Blocks for Analgesia After Off-pump Cardiac Surgery

This study aims to compare the analgesic effects of erector spinae plane block versus Superficial Parasternal Intercostal Plane Block block along with rectus sheath block after off-pump cardiac surgery

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Analgesia Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine

Cairo, Shebin Elkom, Egypt

About this study

General anaesthesia will be used for all patients. induction by midazolam 0.05-0.1 mg/kg, fentanyl 2-5 µ/kg, propofol 1-2 mg/kg, and atracurium 0.5 mg/kg for intubation. Maintenance by sevoflurane in oxygen-air mixture. regional blocks will be used after the induction of anaesthesia. Intraoperative analgesia will be maintained by fentanyl infusion 1-2 µ/kg/h while morphine sulphate 2.5-5mg will be used as rescue analgesia when pain score>4 beside acetaminophen 1000 mg /6 hours

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • American Society of anaesthesiologists physical status classification II-III
  • Elective off-pump cardiac surgery

Exclusion criteria

  • Cognitive impairment
  • Allergy to local anaesthetics
  • Renal and/or hepatic dysfunction
  • Ejection fraction< 45%

Treatment and study plan

Erector spinae plane block

Other

Erector Spinae Plane Block

Superficial Parasternal Intercostal Plane Block combined with Rectus Sheath Block

Other

Superficial Parasternal Intercostal Plane Block combined with Rectus Sheath Block

Primary outcomes

  1. Total opioid consumption

    Time frame: Perioperative.

    µg and mg

Secondary outcomes

  1. Pain intensity at rest and exercise

    Time frame: Perioperative.

    Visual analogue score: a score from 0 to 10(0= no pain and 10 the worst imaginable pain)

  2. Extubation time

    Time frame: Perioperative

    minutes

  3. Duration of post anaesthesia care unit stay

    Time frame: Perioperative

    minutes

  4. Postoperative nausea

    Time frame: Perioperative

    number (%)

  5. Postoperative vomiting

    Time frame: Perioperative

    number (%)

  6. Duration of hospital stay

    Time frame: Postoperative up to 4 weeks

    days

Sponsors and collaborators

Lead sponsor

Abd-Elazeem Abd-Elhameed Elbakry

Other

Registry information

Official study title

Analgesic Effects of Erector Spinae Plane Block Versus Superficial Parasternal Intercostal Plane Block Combined With Rectus Sheath Block After Off Pump Cardiac Surgery: A Randomised Trial

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Mar 10, 2023
Registry last updated
May 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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