Comparing a Monthly Replacement Lens Versus a Daily Disposable Lens

This was a non-dispensing, randomized, double-masked, crossover study. Participants wore 2 different contact lenses bilaterally over 4 study visits, all conducted on the same day. Estimated duration of involvement for each participant was 4 hours.

Inclusion criteria

• Were 17 to 40 years of age and have full legal capacity to volunteer;
• Had read and signed an information consent letter;
• Were willing and able to follow instructions and maintain the appointment schedule;
• Were habitual daily wearers of spherical single vision soft contact lenses to correct for distance vision in each eye
• Were correctable to a visual acuity of 20/20 or better (in each eye) with sphero-cylindrical subjective refraction;
• Had an astigmatism of ≤ 0.75DC in subjective refraction;
• Could be fit with the study contact lenses with a power between -1.00 and -6.00DS; this translates to best corrected vision sphere refraction that vertexes to a CL power between -1.00 and -6.00 (inclusive) at screening visit.
• Demonstrated an acceptable fit with the study lenses.

Exclusion criteria

• Had taken part in another clinical research study within the last 14 days;
• Were currently habitual wearers of toric, multifocal or monovision lenses.
• Had worn any rigid contact lenses in the past 6 months
• Were an extended lens wearer (i.e., sleeping with their lenses)
• Had a difference of ≥1.5 D in best vision sphere subjective refraction between eyes;
• Had amblyopia and/or distance strabismus/binocular vision problem;
• Had any known active ocular disease, allergies and/or infection;
• Had a systemic condition that in the opinion of the investigator may affect a study outcome variable;
• Were using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable;
• Had a known sensitivity to the diagnostic pharmaceuticals to be used in the study;
• Had undergone refractive error surgery or intraocular surgery;
• Were a member of CORE directly involved in the study.