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OpenTrials
Completed

NCT Number: NCT04064619

Compare Sudden Stopping and Weaning of Anticholinergics in Recurrence of OAB Symptoms

Our study included 60 patients with idiopathic OAB and treated with solifenacin 5mg twice daily for one month. After improvement of their condition, we divided the responders into 2 groups, group I stopped the drug suddenly, while group II underwent gradual weaning of the drug.

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Key information

Conditions

Voiding Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Beni-Suef University

Banī Suwayf, Beni Suweif Governorate, 11371, Egypt

About this study

We started an open-label, prospective, two-arm, randomized controlled trial at Beni-Suef University, from January 2018 to January 2019, including 60 patients suffering from OAB symptoms. Patients were recently diagnosed with idiopathic OAB which was not treated prior to enrollment. All participants signed written informed consents. The study protocol was approved by the ethics committee of our faculty. Patients were allocated into 2 equal groups (30 patients in each group) according to a computer-generated random numeric table after exclusion of those who are not eligible or refused to be included in the study

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • OAB patients.
  • Recently diagnosed.

Exclusion criteria

  • Previous trials of treatment
  • UTI, stones, tumors, or Infravesical obstruction.

Treatment and study plan

Solifenacin Succinate 5 MG

Drug

gradual weaning of drug vs. stopping

Other names: vesicare

Primary outcomes

  1. improvement

    Time frame: 1 month

    decrease voiding times

Secondary outcomes

  1. recurrence of symptoms

    Time frame: 3 months

    increase in voiding times after improvement

Sponsors and collaborators

Lead sponsor

Beni-Suef University

Other

Registry information

Official study title

Recurrence of Symptoms of Overactive Bladder After Weaning Versus Sudden Stopping of Anticholinergics

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Aug 22, 2019
Registry last updated
Aug 22, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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