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NCT Number: NCT07230470

Comparative Study of LoKomat® Exoskeleton VS C-Mill® Treadmill for Gait Recovery in Rehabilitation.

The use of robotic technology for the treatment of gait in neurological pathologies has provided different results in scientific evidence. In patients with some types of acquired brain damage, such as stroke, the use of Lokomat® therapy can bring improvements in aspects such as gait speed and balance, among other parameters and report greater functional recovery in subacute patients with greater deterioration. Similarly, the use of another technological element such as the C-Mill® reports improvements in various aspects of ambulation and balance in gait treatments for stroke patients. Likewise, the impact on the person's recovery is not only beneficial for gait rehabilitation, but also improves the perception of well-being, which can be positive in the process of readaptation to daily life.

The effect of both treatments for gait rehabilitation in adults with stroke and their impact on quality of life in the neurorehabilitation clinic will be studied.

adults with stroke and their impact on quality of life at the Lescer neurorehabilitation clinic Lescer, Madrid (Spain). Participants will be assessed at baseline, 4 weeks, 8 weeks and 12 weeks.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universidad Pontificia de Salamanca

Salamanca, 37002, Spain

Location status: Recruiting

Location contact

Jorge Velázquez Saornil, PhD.

CONTACT

[email protected]

923277000

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of stroke (haemorrhagic and/or ischaemic) by a specialist physician. .
  • Subjects who are cognitively capable and who sign the informed consent form.

Exclusion criteria

  • Severe cognitive impairment (Mini-Mental State Examination < 24.), or impairment that prevents correct understanding of the correct understanding of the messages and explanatory orders of the treatment and its conditions.
  • Diagnosis of concomitant neurological diseases and craniocerebral trauma. cranioencephalic trauma.
  • Other diseases that interfere with the gait process (e.g. disabling arthritis or arthrosis, other neurological diseases, other neurological diseases).

disabling arthritis or osteoarthritis, other concomitant neurological diseases, etc.).

  • Contraindications of the robotic tools themselves.

Treatment and study plan

Lokomat®

Device

To compare the effectiveness of gait rehabilitation work in adult stroke patients using the Lokomat® tool vs.

stroke with the C-Mill® tool

C-Mill

Device

Exoelectric walking aid for patients who have suffered a stroke

Primary outcomes

  1. quality of life scale

    Time frame: 12 weeks

    QoL39 scale. 0 minimum - 100 maximum (higher scores mean a better outcome).

  2. Spasticity index

    Time frame: 12 weeks

    Tardieu scale 0 min - 5 max (higher scores mean a worse outcome).

Study contacts

Contact information is provided by the study sponsor or research team.

Jorge V Velázquez Saornil, PhD.

CONTACT

[email protected]

655909940

Sponsors and collaborators

Lead sponsor

Universidad Pontificia de Salamanca

Other

Registry information

Official study title

Comparative Study of Working With the LoKomat® Exoskeleton VS C-Mill® Treadmill for Gait Recovery in Rehabilitation and Improvement of Quality of Life in Adult Stroke Patients. Randomised Clinical Trial.

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 17, 2025
Registry last updated
May 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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