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NCT Number: NCT07687290

Comparative Study Between Pericapsular Nerve Group Block (PENG) And Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block for Positioning Analgesia Prior to Spinal Anesthesia in Hip Fracture Patients

To evaluate and compare the effectiveness of the Pericapsular Nerve Group (PENG) block alone versus the PENG block combined with the Lateral Femoral Cutaneous Nerve (LFCN) block in providing adequate analgesia for patient positioning during spinal anesthesia in individuals undergoing surgery for hip fracture.

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Key information

Conditions

Hip Fracture Surgeries

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Hip fractures are common among adult patients and often necessitate urgent surgical intervention. Positioning these patients for spinal anesthesia in sitting position is often difficult due to intense pain from the fracture. PENG block is a novel regional technique that targets the articular branches of the femoral nerve, obturator nerve, and accessory obturator nerve, providing excellent anterior hip analgesia sparing the motor function. It is performed under ultrasound guidance and has shown promising results in perioperative pain management. By combining LFCN block with the PENG block, more complete sensory blockade may be achieved. The effectiveness of this combination has not yet been adequately studied, particularly regarding positioning for spinal anesthesia. Therefore, this trial aims to compare the analgesic efficacy of PENG block alone versus PENG +LFCN block in this specific context.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18-70 years.
  • ASA I-II.
  • Confirmed primary unilateral hip fracture.
  • Scheduled for surgery under spinal anesthesia.
  • Patients able to provide informed consent.

Exclusion criteria

  • Allergy to local anesthetics.
  • Coagulopathy or on anticoagulant therapy.
  • Infection at injection site.
  • Pre-existing neurological deficits in the lower limbs.
  • Multiple trauma or polytrauma (If other injuries might interfere with positioning or pain scoring).
  • Previous surgery on the ipsilateral hip affecting anatomy or nerve distribution.

Treatment and study plan

PENG block

Procedure

Pericapsular Nerve Group Block

LCFN block

Procedure

Lateral Femoral Cutaneous Nerve block

bupivacaine 0.25%.

Drug

0.25% of Bupivacaine (Bupivacaine 0.5% is added to Lidocaine 2% in the same volume)

Xylocaine 2 %

Drug

local infilteration at the insertion site

Primary outcomes

  1. To compare the time taken to achieve optimal positioning for spinal anesthesia in both groups

    Time frame: from initiation of patient positioning until optimal positioning is achieved during the spinal anesthesia procedure

    time taken in seconds for positioning for spinal anesthesia 15 minutes post- block

Secondary outcomes

  1. To assess Numerical Rating Pain Score in both groups at 0,5,10 and 15 minutes post block

    Time frame: at baseline (0 minutes) and at 5,10 and 15 minutes after completion of the block

    It refers to the common method used in healthcare where patients rate their pain on a scale from 0 to 10 (0 = No pain 10 = Worst pain imaginable).

  2. To assess patient satisfaction and comfort during positioning using Likert scale

    Time frame: during patient positioning 15 minutes after completion of the block

    5-Point scale (1=strongly disagree and 5=strongly agree). The participants measure it 15 minutes post- block during positioning for spinal anesthesia

  3. To monitor mean arterial blood pressure

    Time frame: at baseline (0 minutes) and at 5,10 and 15 minutes after completion of the block

    Comparing mean arterial blood pressure between the 2 groups by millimeter of mercury (mmhg) at 0,5,10 and 15 minutes post-block.

  4. To monitor heart rate

    Time frame: At baseline (0 minutes) and at 5,10 and 15 minutes after completion of the block

    Comparing the heart rate ( by beats per minute) in the 2 groups at 0,5,10 and 15 minutes post-block.

Study contacts

Contact information is provided by the study sponsor or research team.

Maha Salah, lecturer

CONTACT

[email protected]

+201007269331

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 7, 2026
Registry last updated
Jul 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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