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OpenTrials
Completed

NCT Number: NCT07263100

Comparative Study Between Intralesional Corticosteroid Injection Alone and Combined Intralesional Corticosteroid Injection With Either Long-pluse Nd YAG or Erbium Yag for Treating Hypertrophic or Keloid Scars

To compare the effectiveness of hypertrophic or keloid scar treatment with either intralesional corticosteroid injection alone or combined intralesional corticosteroid injection with either long-pulse ND YAG or Erbium YAG

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Key information

Conditions

Hypertrophic Scar Cicatrix Cicatrix, Hypertrophic Collagen Diseases Connective Tissue Diseases Fibrosis Keloid LASER Pathologic Processes Pathological Conditions, Signs and Symptoms Skin and Connective Tissue Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Somdech Phra Nangchao Sirikit Hospital

Sattahip, Changwat Chon Buri, 20180, Thailand

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Individual with hypertrophic or keloid scars on any location
  • Size of hypertrophic or keloid scars not larger than 20 cms in diameter

Exclusion criteria

  • Any topical or procedural treatment on scar in last 6 months
  • Current corticosteroid use
  • Bleeding disorders or coagulopathies
  • Pregnancy or nursing
  • Chronic kidney diseases
  • Chronic liver diseases

Treatment and study plan

Triamcinolone acetonide injection

Drug

Long-pulse ND YAG and Erbium YAG laser device: Fotona Dynamis

Fotona dynamis: Long pulse Nd YAG + Er YAG laser

Device

Intralesional corticosteroid injection combine with long-pulse Neodynium-doped Yttrium Aluminium Garnet Laser (Nd-YAG) (IL KA + ND YAG)

Primary outcomes

  1. Vancouver scar scale

    Time frame: 5 months

    Vancouver scar scale to evaluate scar severity of keloid scar assessing 4 variations including vascularity, pigmentation, pliability, height scoring range from 0-13 (the more scores resembling the more severity)

Secondary outcomes

  1. Japan Scar Workshop Scar Scale

    Time frame: 5 months

    Japan Scar Workshop Scar Scale to evaluate scar severity of keloid scar assessing 2 main domains (risk factors and presenting symptoms) by 2 tables

    • Classification scoring range 0-5 = matured scars 6-15 = hypertrophic scars 16-25 = keloids
    • Evaluation for treatment & follow ups scoring range from 0-18 (the more scores resembling the more severity)

Sponsors and collaborators

Lead sponsor

Somdech Phra Nangchao Sirikit Hospital

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Dec 4, 2025
Registry last updated
Dec 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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