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Completed

NCT Number: NCT04937231

Comparative Effects of Aerobic Exercises, Resistance Training and Combined Training on Heart Failure Patients

To compare the effectiveness of aerobic training and resistance training and combined training on heart failure patients.

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Key information

Conditions

Heart Failure Cardiovascular Diseases Heart Diseases

Age range

35 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Rawalpindi Institute of Cardiology

Rawalpindi, Punjab Province, 44000, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Heart failure patients with ejection fraction greater than 35%

Exclusion criteria

  • Patients with unstable angina
  • Patients who had severe pain in the lower limbs
  • Patients with Blood pressure greater than 190/120mmHg were excluded
  • Patients who had positive contraindication for cardiac rehabilitation were not admitted in this study

Treatment and study plan

aerobic exercises

Other

For Week 1 and 2 : Treadmill 3-5days/weeks

Intensity:

50-70 vo2 peak Or HRR 60-80% Duration of 10-20 minutes For Week 3 and 4; Cycle ergometer 3-5days/weeks

Intensity:

50-70 vo2 peak Or HRR 60-80% Duration of 30-40 minutes

Resistance Exercises

Other

For Week 1 and 2; 2 x 10 rep (unilateral leg press) 4x 12 reps (Bilateral leg press

1 x 8 rep ( unilateral arm curls For Week 3 and 4; 1 x 10 reps Shoulder press

1 x15 rep Bilateral knee extension

1 x 10 reps Bilateral arm curls

combined training

Other

For Week 1 and 2; Aerobic exercise on Treadmill along with dumbbell to perform upper limb exercises (biceps curls, side curls extensions, upright row, back fly) and used Thera band to perform lower limb exercises for 10-20 minutes For Week 3 and 4; Aerobic exercise on Treadmill along with dumbbell and Thera band to perform upper limb and lower limb exercises for 30-40 minutes

Primary outcomes

  1. Hospital Anxiety and Depression Scale

    Time frame: 4th week

    Hospital Anxiety and Depression Scale (HADS) is a 14-item scale with seven items each for anxiety and depression subscales. Scoring for each item ranges from zero to three. A subscale score >8 denotes anxiety or depression. Changes from the Baseline will be measured.

  2. Minnesota living with heart failure questionnaire

    Time frame: 4th week

    Minnesota living with heart failure questionnaire (MLHFQ) is a self-administered, 21-item disease-specific instrument for patients with heart failure. MLHFQ is an instrument which has been widely used to assess quality of life among heart failure patients. Each item is scored in a 6-point Likert Scale (0 to 5), thus the total score could range from 0 to 105, with higher scores indicating more significant impairment in health-related quality of life. The MLHFQ has two domains; physical domain (eight items, score range from 0 to 40) and emotional domain (five items, score range from 0 to 25). Changes from the Baseline will be measured

  3. 6 Min walk test (Distance in meters)

    Time frame: 4th Week

    Changes from the baseline, 6 Min Walk Distance (6 MWD) was used to measure Functional capacity. It is a sub maximal exercise test which can aid in assessing functional capacity of patients with cardiopulmonary diseases, in this test we find out the maximum distance in meters which an individual covers in 6 min without any support.

  4. Peak VO2 with formula

    Time frame: 4th Week

    A generalized equation can be used to determined Peak rate of oxygen consumption (peak VO2). The generalized equation can be used to accurately estimate mean peak VO2 from mean 6 MWD, among groups of patients with diverse diseases without the need for cardiopulmonary exercise testing. The equation is:

    Mean peak VO2(ml/kg/mins) = 4.948 + 0.023*Mean 6 MWD (meter) Changes From the Baseline will be measured.

  5. Heart Rate/Pulse Rate

    Time frame: 4th Week

    Changes from baseline, Pulse rate was measured per minute through pulse oximeter. Crossly it was measure by Chest belt (Polar Heart Rate monitors). Changes from the Baseline will be measure.

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Jun 23, 2021
Registry last updated
Oct 20, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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