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Completed

NCT Number: NCT01055470

Comparative Clinical Trial of Lornoxicam to Diclofenac in Patients of Osteoarthritis of Knee Joint.

The purpose of this study was to compare the pain relieving action of the lornoxicam and diclofenac in patients of OA knee.

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Key information

Conditions

Osteoarthritis of Knee Joint

Age range

25 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sir Takthasinhji General Hospital

Bhavnagar, Gujarat, 364001, India

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Newly diagnosed patient aged between 25 to 65 yrs of either gender suffering from osteoarthritis of knee according to criteria given by American College of Rheumatology
  • Informed consent obtained from the patient.

Exclusion criteria

  • Patients with any other systemic llness,
  • Patients with pregnancy and lactation,
  • Patients taking other drugs like lithium[4], digoxin, methotrexate, anticoagulants, antidiabetics, diuretics,
  • Patients with H/O hypersensitivity to NSAIDs,
  • Patients who had consumed any analgesics in last 1 month

Treatment and study plan

Diclofenac

Drug

Tab. Diclofenac 50 mg 12 hrly, orally, in morning and in evening after taking food for 3 months.

Lornoxicam

Drug

Tab. Lornoxicam 4 mg , orally, 8 hourly after taking food in morning , in noon and evening for 3 months.

Primary outcomes

  1. Difference in reduction in reading of Wong Baker face pain scale and in time of 100 meters walking test

    Time frame: 3 months

Secondary outcomes

  1. To monitor side effects of study drugs.

    Time frame: 3 months

Sponsors and collaborators

Lead sponsor

Government Medical College, Bhavnagar

Other

Registry information

Official study title

Open, Randomized, Controlled Clinical Trial of Lornoxicam as Compared to Diclofenac in Osteoarthritis of Knee Joint in Patients of Tertiary Care Hospital of Gujarat.

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Jan 25, 2010
Registry last updated
Jan 25, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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