NCT Number: NCT07099040
The incidence of cognitive impairment and its burden are increasing with a rapidly ageing population. In Singapore, the prevalence of dementia among older adults aged 60 and above is approximately 10%, which will translate to approximately 152,000 older adults living with dementia by the year 2030. Using 2013 data as estimates, the total annual cost of dementia was already estimated at S$532 million while cost per person was estimated at S$10,245 per annum, and a further increase in corresponding costs is expected through 2030 with the projection of increase in persons with dementia (PWDs). There is thus an urgent need for (i) effective, scalable, and sustainable interventions that are widely accessible to detect and delay cognitive decline and frailty in our community-dwelling older adults, and (ii) providing support for their caregivers. This study aims to test the feasibility of a community-based multi-domain intervention for detecting and delaying cognitive impairment for the older population.
Trial opening soon.
Get Notified60 year and older
All sexes
Interventional
Not applicable
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Older Adults:
Caregivers:
Service providers:
Youth Volunteers:
Exclusion criteria
Older adults
Caregivers:
Care providers:
Psychoeducation will be provided for enrolled participants and their caregivers by Community Resource, Engagement & Support Team (CREST). Visits from CREST teams will be provided on an ad hoc basis, based on older adult participants' needs and circumstances.
Health coaching aims to control risk factors of dementia by community nurses (CMNs) and wellbeing coordinators (WBCs). These include addressing chronic conditions and lifestyle aspects (diet, exercise, habits stress management, and sleep). Care recipients are encouraged to proactively manage their health journey and establish Specific, Measurable, Achievable, Relevant, and Time-bound (SMART) goals with the support of WBCs and CMNs. This multi-faceted approach has the potential to not only address older individuals' immediate health concerns but also foster long-term lifestyle changes. The frequency of visits are once or twice a month, depending on recipients' health status and cognitive functions.
Flexible scheduling is based on individual needs and community nurses' usual practice at the Community Health Post at AACs.
Physical Activity that focuses on improving resistance and balance for care recipients. Physical activity will be conducted 2 times/week at the Active Ageing Centres (AACs) with care recipients for a duration of 1-hour and 1-2 times/week at home.
Cognitive activity will be delivered to enrolled care recipients by Community Resource, Engagement & Support Team (CREST) and AAC staff. With the incorporation of using SilverPad as part of the cognitive activities, care recipients will undergo 1-hour weekly cognitive activity. Youth volunteers will also be engaged to help facilitate the sessions.
This will be augmented with additional 1-2 times weekly home-based training sessions supervised by caregivers.
Time frame: From enrollment to the end of month 6
The MoCA (Montreal Cognitive Assessment) scoring ranges from 0 to 30, with a higher score indicates better cognitive function.
Time frame: From enrollment to the end of month 6
The Short Physical Performance Battery (SPPB) assesses lower extremity function in older adults by evaluating standing balance, gait speed, and repeated chair stands, with scores ranging from 0 to 12, where higher scores indicate better function.
Time frame: From enrollment to the end of month 6
The FRAIL scale (Fatigue, Resistance, Ambulation, Illnesses, and Loss of weight) is a clinical screening tool used to identify frailty in older adults.
Scoring breakdown:
Higher scores indicate worse outcomes/greater frailty:
The five components are scored as follows:
Time frame: From enrollment to the end of month 6
EuroQol 5-Dimension 5-Level (EQ-5D-5L)
For the individual dimension scores (Mobility, Self-care, Usual activities, Pain/discomfort, Anxiety/depression):
Time frame: From enrollment to the end of month 6
For the EuroQol Visual Analogue Scale (EQ VAS):
Time frame: From enrollment to the end of month 6
The Zarit Burden Interview-12 (ZBI-12) or Short Version of Zarit Burden Interview:
Scoring interpretation:
Time frame: From enrollment to the end of month 6
Each item in iADL is rated based on the person's ability to perform the task independently, with some versions scoring:
0 = unable or needs help
1 = independent
Total scores range from 0 (low function, dependent) to 8 (high function, independent).
Time frame: At the end of months 2, 4, and 6
AIM has 4 items describing participants' acceptance of the intervention. Each item has 5 possible options, with scoring
Time frame: At the end of months 2, 4, and 6
IAM has 4 items describing participants' acceptance of the intervention. Each item has 5 possible options, with scoring
Time frame: At the end of months 2, 4, and 6
FIM has 4 items describing participants' acceptance of the intervention. Each item has 5 possible options, with scoring
Time frame: Month 6
Time frame: Month 6
AIM has 4 items describing participants' acceptance of the intervention. Each item has 5 possible options, with scoring
Time frame: Month 6
IAM has 4 items describing participants' acceptance of the intervention. Each item has 5 possible options, with scoring
Time frame: Month 6
FIM has 4 items describing participants' acceptance of the intervention. Each item has 5 possible options, with scoring
Time frame: Feasibility outcome - Caregivers' perceptions of the intervention, collected from qualitative interview
Time frame: From enrollment to the end of month 6
AIM has 4 items describing participants' acceptance of the intervention. Each item has 5 possible options, with scoring
Time frame: Month 6
Contact information is provided by the study sponsor or research team.
Singapore General Hospital
Other
IMPlementation stRategiEs for Scalability and Sustainability - Multidomain INterventions in a Structured Care Pathway to Detect and Delay Cognitive Decline in Community-dwelling Older Adults (IMPRESS-MIND2S): Pilot Test
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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