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Active, Not Recruiting

NCT Number: NCT07375459

Community-based Mobile-assisted Brief Intervention for Smoking Cessation

The goal of this pilot trial is to evaluate the feasibility of a mobile-assisted brief intervention for smoking cessation in community-based individuals in Singapore. Specific aims include:

1. To assess how many eligible individuals accept the invitation to participate in the trial 2. To assess the retention of the participants through 6 months after treatment initiation 3. To assess the acceptability of the intervention in terms of participants' engagement and ratings 4. To examine the intervention effect on abstinence outcomes

Participants will be randomly assigned to either the intervention group or control group and followed for 6 months from randomisation.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Smoking &Amp; Tobacco Cessation Behavior Health Behavior Smoking Smoking Cessation Tobacco Use Cessation

Age range

21 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

National University of Singapore

Singapore

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 21 to 80 years
  • Smoked at least one cigarette daily
  • Able to communicate and read in English or Chinese
  • Own a smartphone with WhatsApp installed

Exclusion criteria

  • Exposed to any smoking cessation treatment in the past 3 months
  • Pregnant women

Treatment and study plan

Brief cessation advice + self-help booklet

Behavioral

Participants will receive brief cessation advice following the AWARD (ask, warn, advise, refer, do-it-again) model and a 24-page self-help booklet.

Opt-out referral

Behavioral

Research personnel will assist the participant in signing up for the I Quit Programme to receive additional cessation support, unless they decline

Mobile chat messaging

Behavioral

Participants will receive personalised chat-based support delivered by a live counsellor for 3 months via WhatsApp. The message will incorporate behaviour change techniques for smoking cessation and mindfulness principles to strengthen participants' capacity to quit smoking.

Primary outcomes

  1. Biochemically validated smoking abstinence rate

    Time frame: 6 months

    Defined as an exhaled carbon monoxide level of <5 parts per million or a negative salivary cotinine test (cut off 30ng/mL)

  2. Recruitment rate

    Time frame: 6 months

    Number of participants divided by the number of eligible subjects

  3. Retention rate

    Time frame: 6 months

    Number of participants completed the follow-up divided by the number of participants

Secondary outcomes

  1. Self-reported 7-day point-prevalence smoking abstinence rate

    Time frame: 3 months

    Being completely smoke-free in the past 7 days

  2. Self-reported 7-day point-prevalence smoking abstinence rate

    Time frame: 6 months

    Being completely smoke-free in the past 7 days

  3. Self-reported smoking reduction rate

    Time frame: 3 months

    Smoking reduction by at least half of the baseline daily number of cigarettes in individuals who continue to smoke

  4. Self-reported smoking reduction rate

    Time frame: 6 months

    Smoking reduction by at least half of the baseline daily number of cigarettes in individuals who continue to smoke

  5. Self-reported quit attempt rate

    Time frame: 3 months

    Serious quit attempt that lasted 24 hours or longer

  6. Self-reported quit attempt rate

    Time frame: 6 months

    Serious quit attempt that lasted 24 hours or longer

  7. Smoking cessation service use rate

    Time frame: 3 months

    Use of any smoking cessation service during the follow-up period

  8. Smoking cessation service use rate

    Time frame: 6 months

    Use of any smoking cessation service during the follow-up period

Sponsors and collaborators

Lead sponsor

National University of Singapore

Other

Registry information

Official study title

Mobile-assisted Brief Intervention for Smoking Cessation in Community-based Setting: a Pilot Randomised Controlled Trial

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Jan 29, 2026
Registry last updated
Jul 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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