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NCT Number: NCT07611682

Community-Based Eye Screening With Structured Referral Tracking for Preventing Avoidable Blindness in Adults in Rawalpindi, Pakistan

This cluster randomized controlled trial aims to evaluate the effectiveness of a Structured Referral Tracking (SRT) intervention in improving referral completion among adults identified with avoidable blindness during community-based eye screening camps in Rawalpindi District, Pakistan. Ten community clusters will be randomized into intervention and control groups. Participants in the intervention group will receive structured referral counseling, weekly reminder calls or messages, and customized referral guidance for eight weeks, while the control group will receive standard referral procedures. The primary outcome is referral completion at a tertiary eye hospital within eight weeks after screening. Secondary outcomes include knowledge regarding avoidable blindness, treatment satisfaction, feasibility, acceptability, and barriers influencing referral completion.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

ACCO Department, Al-Shifa Trust Eye Hospital, Rawalpindi

Rawalpindi, Punjab Province, 46600, Pakistan

About this study

Avoidable blindness remains a major public health challenge in low- and middle-income countries, including Pakistan. Community-based eye screening camps are commonly used to identify individuals with visual impairment and eye diseases requiring treatment; however, referral completion to tertiary eye care facilities remains poor. Many patients fail to attend referral hospitals because of limited awareness, lack of follow-up, transportation barriers, and uncertainty regarding treatment procedures.

This study aims to evaluate the effectiveness and implementation of a Structured Referral Tracking (SRT) intervention in improving referral completion among adults identified with avoidable blindness during community-based eye screening camps in Rawalpindi District, Pakistan.

The study will use a cluster randomized controlled trial design. Ten community clusters (union councils) from five tehsils of Rawalpindi District will be selected using multistage random sampling. Clusters will be randomized into intervention and control arms. Participants attending eye screening camps who are diagnosed with eye conditions requiring referral to a tertiary eye hospital will be enrolled after informed consent.

Participants in the intervention arm will receive a multi-component Structured Referral Tracking intervention consisting of referral counseling, weekly reminder calls or mobile messages, visual educational material, and customized referral guidance regarding hospital location, estimated costs, and required documents. Participants in the control arm will receive standard referral procedures consisting of routine counseling and referral slips without structured follow-up.

The primary outcome will be referral completion at the tertiary eye hospital within eight weeks after screening, verified through hospital attendance records. Secondary outcomes will include knowledge regarding avoidable blindness, treatment satisfaction, feasibility and acceptability of the intervention, and barriers influencing referral completion.

The findings of this study are expected to provide evidence regarding the effectiveness and feasibility of structured referral tracking systems for improving eye care service utilization and reducing avoidable blindness in Pakistan.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 18 years or above
  • Individuals diagnosed with visual impairment or eye conditions requiring referral to a tertiary eye care facility
  • Permanent residents of Rawalpindi District, Pakistan
  • Willing and able to provide informed consent

Exclusion criteria

  • Individuals already undergoing treatment for the identified eye condition
  • Individuals requiring emergency ophthalmic care
  • Severe systemic or physical illness limiting follow-up
  • Individuals unable to provide informed consent

Treatment and study plan

Structured Referral Tracking (SRT)

Behavioral

A multi-component referral tracking intervention including referral counseling, weekly reminder calls or mobile messages, visual educational material, and customized referral guidance to improve referral completion after community eye screening.

Primary outcomes

  1. Referral Completion Rate Verified Through Hospital Records

    Time frame: Within 8 weeks after community eye screening

    Proportion of referred participants who complete referral visits at the tertiary eye hospital, verified through hospital attendance records.

Secondary outcomes

  1. Knowledge Score on Avoidable Blindness Questionnaire

    Time frame: Baseline and 8 weeks after screening

    Participant knowledge regarding avoidable blindness and eye health assessed using a structured questionnaire developed for the study.

  2. Participant Acceptability of Structured Referral Tracking Assessed Using Structured Feedback Questionnaire

    Time frame: Within 8 weeks after screening

    Participant acceptability of the Structured Referral Tracking intervention assessed using a structured feedback questionnaire regarding usefulness and satisfaction with reminder communication.

  3. Barriers Influencing Referral Completion Assessed Using Structured Barrier Assessment Questionnaire

    Time frame: Within 8 weeks after screening

    Barriers and facilitators influencing referral completion assessed using a structured questionnaire among referred participants.

Other outcomes

  1. Participant Treatment Satisfaction Score Using Structured Satisfaction Questionnaire

    Time frame: Within 8 weeks after screening

    Participant-reported satisfaction regarding referral services and treatment received at the tertiary eye hospital assessed using a structured satisfaction questionnaire.

  2. Feasibility of Structured Referral Tracking Assessed by Reminder Delivery and Follow-up Completion Rates

    Time frame: Within 8 weeks after screening

    Feasibility of the intervention assessed through successful delivery of reminder messages/calls and completion of scheduled follow-up procedures.

Study contacts

Contact information is provided by the study sponsor or research team.

Khizar Nabeel, PHD (In progress)

CONTACT

[email protected]

+923455096776

Sponsors and collaborators

Lead sponsor

Health Services Academy, Islamabad, Pakistan

Other

Collaborators

  • Al-Shifa Trust Eye Hospital

Registry information

Official study title

Community-Based Eye Screening With a Structured Referral Tracking Intervention for the Prevention of Avoidable Blindness Among Adults in Rawalpindi District, Pakistan

Acronym: SIGHT

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 28, 2026
Registry last updated
Jun 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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