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OpenTrials
Completed

NCT Number: NCT01148485

Community-acquired Methicillin-Resistant Staphylococcus Aureus Carriage Among Athletes

There are only very few data about the prevalence of CA-MRSA in France and no in athletes. In USA, the clone USA300 is widely disseminated and in Europe the clone ST80 predominates. The aim of the study was to study the carriage of S. aureus in athletes in a French county (Limousin) and to evaluate the proportion of CA-MRSA. The athletes will be met during their training, each one will fill-in a clinical information questionnaire. Nasal, throat, inguinal and skin lesions swab samples will be performed. The antibiotic susceptibility profile of the Staphyloccocus aureus strains isolated will be performed as well as the detection of the PVL gene. Strains will also be typed by different molecular methods (PGFE (Pulsed Gel Field Electrophoresis), SCCmec type (Staphylococcal Chromosome Cassette mec), and MLST (MultiLocus Sequence Typing)). The CIC (Clinical Investigation Center) of the Limoges University Hospital will be in charge of the inclusions of the athletes. The sample analysis will be centralized and performed at the Laboratory of Bacteriology of the Limoges University Hospital. A Clinical Research Officer of the Limoges University Hospital will be in charge of the survey of the study and will organize monthly meetings with all the participants of the study.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult patients (over 18),
  • belonging to a sport club of Limousin, practicing rugby, wrestling, basket-ball, volley-ball, hand-ball, fence, martial art, football, weight lifting, and base-ball.
  • Patient having signed in a free way and lit his consent to participate in this study

Exclusion criteria

  • clinical information questionnaire not possible to fill,
  • swab sample not possible to realize.

Treatment and study plan

Nasal, throat, inguinal and skin lesions swab samples will be performed

Other

Nasal, throat, inguinal and skin lesions swab samples will be performed

Primary outcomes

  1. Presence of Methicillin-Resistant Staphylococcus aureus in the samples.

    Time frame: 1 year

    An athlete is defined as a carrier if at least one strain of Staphylococcus aureus is isolated from one of these samples.

    A MRSA carrier is defined if the resistance to methicillin has been found for the S. aureus strain isolated in the patient.

Secondary outcomes

  1. Comparison of the MRSA prevalence in athletes according to the sport

    Time frame: 1 year

    Comparison of the MRSA prevalence in athletes according to the sport.A strain is considered as PVL positive if the gene encoding the PVL was detected by PCR.

Sponsors and collaborators

Lead sponsor

University Hospital, Limoges

Other

Registry information

Official study title

Community-acquired Methicillin-Resistant Staphylococcus Aureus Carriage Among Athletes: a Study in Limousin. : CA-MRSA

Acronym: PSARM-S

Important dates

Study start
2011
Primary completion
2011
Study completion
2011
First posted
Jun 22, 2010
Registry last updated
Nov 1, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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