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NCT Number: NCT01935388

Common Canister Protocol for Inhaler Administration in Mechanically Ventilated Patients

Many hospitals employ a common canister inhaler protocol in patients that do not require mechanical ventilator support. Common canister refers to a single inhaler paired with standardized cleaning methods for use on more than one patient. Small reports suggest that this method does not pose an increased infectious risk and is associated with significant cost savings.

Common canister protocols offer a solution to the discordance between inhaler sizes and average inpatient use of the drugs. Metered dose inhaler canisters are contain enough drug for several days to weeks of daily use. However, the average length of stay for most inpatients is only several days. Therefore, most inpatients do not use all of the canister contents, an unused resource that is potentially wasted.

The common canister approach has not been previously described in mechanically ventilated patients (people requiring intensive care unit admission on breathing machines). This study aims to assess the safety of common canister utilization by assessment and comparison of infection rates in the study and control group.

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Key information

Conditions

Ventilator Associated Pneumonia Asthma Bronchial Diseases Chronic Disease Cross Infection Disease Attributes Healthcare-Associated Pneumonia Hypersensitivity Hypersensitivity, Immediate Iatrogenic Disease Immune System Diseases Infections Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pneumonia Pneumonia, Ventilator-Associated Pulmonary Disease, Chronic Obstructive Respiratory Hypersensitivity Respiratory Tract Diseases Respiratory Tract Infections

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Barnes-Jewish Hospital

St Louis, Missouri, 63110, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • mechanically ventilated patients prescribed bronchodilator therapy in a medical intensive care unit

Exclusion criteria

  • lung transplant
  • neutropenic
  • contact isolation

Treatment and study plan

Common canister

Other

Drug administration via a shared canister with a standardized cleaning protocol.

Primary outcomes

  1. Ventilator-associated pneumonia (VAP)

    Time frame: 48 hours after intubation

    Pneumonia that developed in association with mechanical ventilation

Secondary outcomes

  1. Inhaler drug cost

    Time frame: During period of mechanical ventilation, which varies depending on patient's severity of illness and reason for intubation; on average may range from 3-5 days.

    Inhaler charges accrued during mechanical ventilation

Sponsors and collaborators

Lead sponsor

Barnes-Jewish Hospital

Other

Registry information

Official study title

Common Canister Protocol for Metered Dose Inhaler Administration in Mechanically Ventilated Patients

Important dates

Study start
2013
Primary completion
2016
Study completion
2016
First posted
Sep 5, 2013
Registry last updated
Oct 7, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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