COMBO Endoscopy Oropharyngeal Airway in Sedated Endoscopic Retrograde Cholangiopancreatography for Patients

Inclusion criteria

• Age ≥18 years；
• The ASA classification ranges from I to III.
• Patients have signed the informed consent form.
• Patients scheduled to undergo sedated ERCP examination;
• The estimated duration of the procedure does not exceed 45 minutes.

Exclusion criteria

• Patients with coagulation disorders, tendency for oral/nasal bleeding, mucosal injury/occupying lesions, or difficult oropharyngeal airway insertion making airway management unfeasible;
• Severe cardiac dysfunction (<4 METs);
• Severe renal insufficiency (requiring preoperative dialysis);
• Child-Pugh class C;
• Diagnosed chronic obstructive pulmonary disease (COPD) or other acute/chronic pulmonary diseases requiring long-term/intermittent oxygen therapy;
• Increased intracranial pressure;
• Upper respiratory tract infections (oral/nasal/pharyngeal);
• Fever (core temperature >37.5°C);
• Confirmed pregnancy or current breastfeeding;
• Allergy to sedatives (e.g., propofol) or medical adhesives;
• Emergency procedures;
• Multiple trauma injuries;
• Peripheral oxygen saturation (SpO2) levels below 95% while breathing room air preoperatively;
• BMI <18.5 or >30 kg/m²;
• Current participation in other clinical trials;
• Other conditions deemed ineligible by investigators.