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Enrolling by Invitation

NCT Number: NCT06882213

Combining Transcranial Direct Current Stimulation and Core Stability Exercise on Trunk in Stroke Patient

To evaluate the effects of the combining transcranial direct current stimulation with core stability exercises on trunk performance in poststroke hemiparetic patients, the secondary outcome is to evaluate the balance and the functional performance of the participants.

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Key information

Age range

55 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Beni suef hospital

Banī Suwayf, 62511, Egypt

About this study

This study will conduct to 60 male and female patients with post stroke hemiparesis with age ranged between 55 to 70 years, the patients will be categorized to two equal groups.

  • Group A (study group): will receive simultaneously a combination of transcranial direct current stimulation combined with core stability exercise.
  • Group B (control group): will receive core stability exercise. All patients will be assessed for trunk performance, balance, and functional performance before and after interventions.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients will be included if they are ≥ 55 years old of both sex, had a first-time right or left stroke within the preceding six months that damaged the cerebral cortex verified by (computed tomography or MRI report, neurological examination, and medical chart).
  • Patients can stand and walk independently.
  • Modified Ashworth Scale (MAS) of upper limb muscle ≤ 1+.
  • All the patients received a conventional physiotherapy program in the acute stage and post-discharge from the hospital.
  • None of the patients participated in any other study or placebo

Exclusion criteria

  • Patients with neurological or orthopedic problems, paralysis neglect, behavioral abnormalities, dementia any shoulder dysfunction before or post-stroke (dislocation or subluxation), or those who using upper limb splints.
  • Recurrent strokes or hemiparesis due to other neurological causes rather than stroke eg .(Brain tumor).
  • Obesity (BMI ≥ 30 kg/m2).

Treatment and study plan

transcranial direct current stimulation

Other

transcranial direct current stimulation

core stability exercise.

Other

core stability exercise.

Primary outcomes

  1. Trunk Impairment Scale (TIS).

    Time frame: up to 8 weeks

    trunk performance will be assessed by Trunk Impairment Scale (TIS).

  2. Berg Balance Scale

    Time frame: up to 8 weeks

    Balance will be assessed by berg balance scale, the balance score ranges from 0 to 56, with lower scores indicating increased risk of balance loss and higher scores indicating improved functional mobility. Time up and go test (TUG)n Score < 10 seconds = normal < 20 seconds = good mobility; can walk outside alone; does not require a walking aid < 30 seconds = walking and balance problems; cannot walk outside alone; requires walking aid

Sponsors and collaborators

Lead sponsor

Beni-Suef University

Other

Registry information

Official study title

Unlocking Trunk Potential After Stroke: A Novel Approach Combining Transcranial Direct Current Stimulation and Core Stability Exercise

Acronym: TCDC

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Mar 18, 2025
Registry last updated
Feb 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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