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NCT Number: NCT06845176

Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery

Kinesthetic motor imagery (kMI) involves imagining the sensations of movement, activating brain regions similar to actual movement execution. It is widely used to maintain or restore motor functions, particularly in rehabilitation. Tendon vibration (TV), which stimulates proprioceptive receptors can also enhance corticospinal excitability and promote neuroplasticity. This project investigates the coupling of kMI and TV through three modalities: simultaneous application, TV application between kMI trials, or pre-application of TV to precondition the nervous system before kMI trials. The effectiveness and quality of kMI will be assessed by corticospinal excitability measurements using transcranial magnetic stimulation and EEG measures. Conducting this study in healthy participants will inform the development of optimized clinical interventions for immobilized or mobility-reduced patients.

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Key information

Conditions

Healthy Volunteer

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

IRMIS-Hôpital Nord

Saint-Etienne, France, 42055

Location status: Recruiting

Location contact

Diana RIMAUD, Docor of science

CONTACT

[email protected]

0477120467 ext. 33

Lenoard FEASSON, PhD

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Men or women aged 18 to 50 years.
  • Affiliated with or beneficiaries of a social security system.
  • Provided written informed consent freely after being informed of the study's purpose, procedures, and potential risks.

Exclusion criteria

  • History of pathology or surgery affecting upper limb motor function within 6 months prior to the study.
  • Chronic neurological, motor, or psychiatric disorders.
  • Use of neuroactive substances likely to alter corticospinal excitability (e.g., hypnotics, antiepileptics, psychotropics, muscle relaxants) during the study period.
  • Contraindications to transcranial magnetic stimulation
  • Simultaneous participation in another interventional study or participation in such a study within 30 days prior to this study.

Treatment and study plan

Tendon vibration (TV)

Device

We use the VIBRAMOOV PHYSIO device which delivers local muscle vibrations at frequencies of 80 Hz and an amplitude of 1 mm.

Kinesthetic motor imagery (kMI)

Other

kMI is a mental technique in which an individual visualizes performing a movement without physically executing it. This process involves the internal representation of the sensations associated with the movement, engaging neural pathways similar to those activated during actual physical movement. kMI stimulates key motor and sensory areas in the brain, promoting neuroplasticity and enhancing motor performance.

Primary outcomes

  1. Optimization of kMI

    Time frame: 30 minutes

    We will measure corticospinal excitability. This will be assessed by the area (in mV.%) under the curve representing the amplitude of motor-evoked potentials (MEPs, in mV) recorded via electromyography, as a function of transcranial magnetic stimulation intensity (in % of the stimulator's maximal output) required to evoke these potentials.

Study contacts

Contact information is provided by the study sponsor or research team.

Diana RIMAUD, Doctor of Science

CONTACT

[email protected]

0477120467 ext. 33

Léonard FEASSON, PhD

CONTACT

[email protected]

04 77 12 03 83 ext. 33

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Saint Etienne

Other

Collaborators

  • Jean Monnet University

Registry information

Official study title

Comparison of Three Modalities of Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery

Acronym: IMVT

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Feb 25, 2025
Registry last updated
Apr 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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