Combined Use of a Novel Cardioplegic Formula With MPS ® Using the MiECC in Isolated CABG Versus OPCABG

A patient group receiving a novel cardioplegic formula with MPS ® (Myocardial protection system) and using the MiECC (Minimal extracorporeal circulation system) when undergoing coronary artery bypass grafting is compared to a retrospective patient group undergoing Off-pump coronary artery bypass grafting.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Complication of Coronary Artery Bypass Graft Complication of Extracorporeal Circulation

Sex eligibility

All sexes

Study type

Observational

Primary location

Herzchirurgie University Hospital Basel

Basel, 4031, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

CABG using MPS® or OPCABG

Exclusion criteria

use of other colloid solution than Cardioplexol ® for MPS®
other inventions than CABG
myocardial infarction <7 days before CABG
patients denial of data use

Treatment and study plan

CABG

Procedure

CABG with application of a myocardial protection system (MPS ®) and using a minimal extracorporeal circulation system (MiECC) or CABG without use of a minimal extracorporeal circulation system (Off-pump coronary artery bypass grafting = OPCABG)

Primary outcomes

assessment of cardial biomarkers as high sensitive troponin T (hs-TrT), Creatinkinase (CK) and Creatinkinase myocardial type (CK-MB)

Time frame: perioperative during hospital stay for CABG

high sensitive troponin T (hs-TrT), Creatinkinase, (CK) Creatinkinase myocardial type (CK-MB)

Secondary outcomes

mortality

Time frame: 30 days after CABG

death after coronary artery bypass grafting
need for intensive care unit

Time frame: perioperative during hospital stay for CABG

duration of stay at intensive care unit
occurence of dysrhythmia

Time frame: perioperative during hospital stay for CABG

rhythm disturbance after CABG

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Registry information

Acronym: OPCBAG

Important dates

Study start: 2010
Primary completion: 2018
Study completion: 2018
First posted: Aug 1, 2018
Registry last updated: Aug 1, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed