Egypt
Asyut, 71515, Egypt
NCT Number: NCT05580094
* compare the safety and efficacy of ultrasound-guided supraclavicular block in addition to general anesthesia in pediatric patients undergoing upper limb superficialization of arteriovenous fistula for hemodialysis. * compare the amount of analgesic consumption as well as vasodilatation of upper limb blood vessels and its implications on the vascular anastomosis.
Looking for future studies?
Notify Me2 year–18 year
All sexes
Interventional
Not applicable
Asyut, 71515, Egypt
Established renal disease is a significant cause of morbidity and mortality in children and has implications for the conduct of general anesthesia (1).
Anesthetic management of pediatric patients is uniquely challenging. A large part of the anesthetic care includes pain management, management of concomitant disease, and risk reduction for adverse events. Perioperative pain management usually involves a multimodal pharmacologic approach to minimize opioid requirements. Regional anesthesia is valuable for postoperative pain control (2).
Postoperative analgesia is dictated by the extent and nature of the surgery. Regional block should be utilized where possible for its opioid-sparing effects. Where morphine infusions are commenced, the dose should be reduced due to the risk of accumulation of active metabolites and resultant opiate toxicity. Non-steroidal anti-inflammatory drugs are always avoided due to their deleterious effects on urine output (3).
Pediatric regional anesthesia is one of the most valuable and safe tools to treat perioperative pain and is an essential part of modern anesthetic practice. It provides excellent pain relief and allows caregivers to use multimodal analgesic techniques and decrease the use of opioids. Upper extremity brachial plexus blocks in children Various approaches to brachial plexus are available. The choice of the block is made depending on the indications. The supra-clavicular approach covers all the surgeries of the humerus and below (4).
The use of regional anaesthesia is mostly associated with vasodilatation which may guard against arterial spasm and may play a role in decreasing the postoperative complication and success of the superficialization of the arteriovenous shunt as a line for hemodialysis.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
induction of general anesthesia by propofol and maintenance sevoflurane.
induction of general anesthesia by propofol and maintenance sevoflurane then the patients will receive the supraclavicular block with bupivacaine 0.5 ml per kg.
Time frame: 6 month postoperative
time in weeks required by fistula to be clinically mature
Time frame: 90 minutes intraoperative
measurment of anesthesia MAC
Time frame: 24 hours postoperative
Time frame: 30 minutes postoperative
RASS score used with -5 = deeply sedated and 4 = highly agitated
Time frame: 24h postoperative
scale of 10 points. zero= no pain and 10 = worest pain
Assiut University
Other
Combined General Anesthesia and Ultrasound Guided Supraclavicular Block Versus General Anesthesia in Pediatric Patients With Chronic Kidney Disease Undergoing Upper Limb Superficialization of Arteriovenous Fistula.
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06546722
Cardiac Surgery, Neurologic Manifestations
Beirut, Lebanon
View Trial DetailsNCT05982392
Neurologic Manifestations, Pain
Karachi, Sindh, Pakistan
View Trial DetailsNCT01307202
Neurologic Manifestations, Pain
Hamilton, Ontario, Canada
View Trial DetailsNCT05374499
Neurologic Manifestations, Pain
Los Angeles, California, United States
View Trial Details