Menoufia university
Menoufia, Egypt
NCT Number: NCT05930171
The investigators are going to evaluate the postoperative analgesic efficacy of combined LESPB and PENG block after hip surgeries.
Looking for future studies?
Notify Me18 year–70 year
All sexes
Interventional
Phase 4
Menoufia, Egypt
Hip surgeries are very common surgeries and has high postoperative pain potential. There are different ways to execute postoperative analgesia and each of them has advantages and disadvantages. As the patients submitted to this procedure are usually older and with multiple comorbidities, analgesia options with better profile of adverse effects should be preferred. Peripheral nerve block with long-acting local anesthetics is very suitable in this situation, in comparison with systemic or neuraxial opioids.
Pain control after total hip arthroplasty (THA) can be challenging because of complex innervation of the hip joint from both the lumbar and sacral nerve plexus. pain was the cause of 12% of unplanned hospital patient admissions, 60% of these patients were admitted for orthopedic concerns. The consequences of severe postoperative pain are prolonged hospital stay, increase hospital readmission, precipitation in the use of opioids with subsequent increase in postoperative nausea and vomiting, and overall low patient satisfaction. Furthermore, postoperative pain can seriously impact the physical and mental health of the patient and lead to secondary complications such as nausea, vomiting, slowed bowel movements, muscle spasms, thrombosis, cardiopulmonary complications and delayed recovery of organ functions.
The hip joint is innervated by the articular branches of multiple nerves that emerge from the lumbosacral plexus (L2-S1). The nerve supply to a specific region of the joint typically corresponds to the innervation of the muscle that crosses it :-
Hip joint capsular innervation was found to consistently involve the femoral and obturator nerves, which supply the anterior capsule, and the nerve to the quadratus femoris, which supplies the posterior capsule.
Lumbar erector spinae plane block (LESPB) local anesthetics spread to lumbar paravertebral space and lumbar nerve roots, reaching the nerves responsible for the innervation of the hip joint lumbar plexus nerves - femoral, obturator and lateral femoral cutaneous nerves - providing analgesia for hip surgery. LESPB can be a block easier to perform than other options for hip surgery analgesia, such as posterior lumbar plexus.
(L-ESPB) is an effective analgesic technique after hip surgeries. However, an insufficient sensorial blockade of the medial part of the thigh which is innervated by the obturator nerve.
The pericapsular nerve group (PENG) block is an ultrasound-guided approach, first described by Giron-Arango et al. for the blockade of the articular branches of the femoral, obturator and accessory obturator nerves that provide sensory innervation to the anterior hip capsule. It has been successfully used as an alternative regional anaesthesia technique for the management of acute pain after hip fracture, but its applications are expanding, suggesting a potential role for analgesia after elective hip surgery.
After all the investigators hypothesize that combination of LESPB and PENG block can be more effective in pain control after hip surgeries.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Combined Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block in Patients Undergoing Hip Surgeries
Other names: Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block
Postoperative conventional analgesia in form of acetaminophen 15 mg/kg/6hrs
Other names: Conventional analgesia
Time frame: at 1 hour after the block
Postoperative pain intensity using Visual Analogue Scale (VAS) (which is over 10 centimeter scale) (where 0 indicates no pain at all , 10 indicates severe pain)
Time frame: at 3 hour after the block
Postoperative pain intensity using Visual Analogue Scale (VAS) (which is over 10 centimeter scale) (where 0 indicates no pain at all , 10 indicates severe pain)
Time frame: at 6 hour after the block
Postoperative pain intensity using Visual Analogue Scale (VAS) (which is over 10 centimeter scale) (where 0 indicates no pain at all , 10 indicates severe pain)
Time frame: at 12 hour after the block
Postoperative pain intensity using Visual Analogue Scale (VAS) (which is over 10 centimeter scale) (where 0 indicates no pain at all , 10 indicates severe pain)
Time frame: at 24 hour after the block
Postoperative pain intensity using Visual Analogue Scale (VAS) (which is over 10 centimeter scale) (where 0 indicates no pain at all , 10 indicates severe pain)
Time frame: assessed at preoperative, postoperative (0,3,6,12,24 hours), Value is averaged of total measurements
Heart Rate
Time frame: assessed at preoperative, postoperative (0,3,6,12,24 hours), Value is averaged of total measurements
Arterial Blood Pressure
Time frame: assessed at preoperative, postoperative (0,3,6,12,24 hours), Value is averaged of total measurements
Arterial Oxygen Saturation
Time frame: 24 hours postoperative
Time to first analgesic administration
Time frame: 24 hours postoperative
Total analgesic requirements in 24 hours postoperative
Time frame: 24 hours after the block
patients will be asked to assess their satisfaction :-
Time frame: 24 hours after the block
Either hematoma, infection, postoperative nausea, vomiting orlocal anesthetic systemic toxicity
Time frame: 1 hour after the block
Block failure (patients still feeling pain immediately after 1 hour from block)
Menoufia University
Other
Analgesic Efficacy of Combined Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block in Patients Undergoing Hip Surgeries
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT04899388
Lumbar Erector Spinae Plane Block, Pericapsular Nerve Group Block (PENG Block)
Zagazig, Sharqia Province, Egypt
View Trial DetailsNCT07652177
Lumbar Erector Spinae Plane Block, Lumbar Microdiscectomy Surgery
Istanbul, Turkey (Türkiye)
View Trial DetailsNCT07639762
Agnosia, Femoral Fractures
Istanbul, Sancaktepe, Turkey (Türkiye)
View Trial DetailsNCT06573931
Agnosia, Analgesia
Tanta, El-Gharbia, Egypt
View Trial Details