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NCT Number: NCT07484737

Combined Effects of MWM and Tendon Gliding Exercises in Smartphone Users With De Quervain's Tenosynovitis

This randomized controlled trial aims to assesses the combined effects of MWM and tendon gliding exercises on hand function in smartphone users with De Quervain's Tenosynovitis, considering hand anthropometric variations.

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Key information

Conditions

DeQuervain's Tenosynovitis

Age range

18 year–25 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Begum Akhtar Rukhsana Hospital (stroke and rehab centre)

Rawalpindi, Punjab Province, Pakistan

Location status: Recruiting

Location contact

maria khalid, MSOMPT

CONTACT

[email protected]

03315369768

sadia wajid, MSOMPT*

CONTACT

sadia wajid, MSOMPT*

PRINCIPAL_INVESTIGATOR

About this study

De Quervain's Tenosynovitis (DQT) is a painful musculoskeletal condition characterized by inflammation of the abductor pollicis longus and extensor pollicis brevis tendons within the first dorsal compartment of the wrist. It is commonly associated with repetitive thumb and wrist movements, with smartphone overuse emerging as a significant contributing factor among young adults.

Mulligan's Mobilization with Movement (MWM) has been shown to correct minor joint malalignments and reduce compressive forces on inflamed tendons, thereby improving wrist kinematics and reducing pain. Tendon gliding exercises enhance tendon excursion, minimize adhesions, and improve synovial fluid circulation, which supports recovery of thumb and wrist function. When combined, these interventions address both mechanical and functional impairments associated with DQT.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient diagnosed with De Quervain's Tenosynovitis (positive Finkelstein's test).
  • Patient having persistent thumb/wrist pain and functional difficulties for a duration of at-least 2 weeks.
  • Patient willing to participate and give informed consent.

Exclusion criteria

  • Patient with history of trauma, fracture, or surgery in the affected wrist or thumb.
  • Patient with neurological disorder affecting the upper limb.
  • Patient with systemic conditions like rheumatoid arthritis or diabetes affecting tendon function.
  • Any other co-morbidity.

Treatment and study plan

MWM + Tendon Gliding Exercises

Other

MWM: Radial glide of 1st MCP with active thumb extension (10 reps × 3 sets, progressed with resistance in weeks 3-4). 2- Tendon Gliding Exercises: Straight hand, hook fist, tabletop, full fist, straight fist (10 reps × 2 sets in weeks 1-2; 3 sets × 15 with resistance band in weeks 3-4).

conventional treatment

Other

1- Wrist ROM (flexion, extension, radial/ulnar deviation, pronation/supination). 2-Thumb ROM (abduction/adduction, flexion/extension, opposition/circumduction). 3-Isometric wrist/thumb strengthening. 4-Strengthening with soft ball, thumb abduction/adduction against resistance. 5-Postural and ergonomic education for smartphone usage

Primary outcomes

  1. Grip Strength Dynamometer

    Time frame: 4 weeks

    It is a valid and reliable tool used for measuring isometric hand grip strength. This objective tool will be used to assess hand muscular performance and functional status in patients with De Quervain's Tenosynovitis. The NOD digital dynamometer has been shown to provide consistent and reproducible readings. Reliability: 0.97 and Validity: 0.94.

  2. Patient-Rated Wrist Evaluation (PRWE) Questionnaire

    Time frame: 4 weeks

    It is a valid and reliable patient-reported outcome measure for assessing wrist pain and functional disability. This tool will be used to evaluate wrist-related limitations in activities of daily living in DQT patients. It includes two subscales: pain and function, making it responsive to clinical changes. Reliability: 0.96 and Validity: 0.88.

  3. Hand Anthropometry (Caliper & Measuring Tape)

    Time frame: Baseline

    These are reliable and valid tools used to measure various hand dimensions, including palm width, thumb length, and wrist circumference. These measurements help understand the influence of hand morphology on grip strength and functional ability in smartphone users with DQT. Reliability: 0.88 and Validity: 0.71.

Study contacts

Contact information is provided by the study sponsor or research team.

maria Khalid, MSOMPT

CONTACT

[email protected]

03315369768

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Combined Effects of Mulligan's Mobilization With Movement and Tendon Gliding Exercises in Smartphone Users With De Quervain's Tenosynovitis.

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 20, 2026
Registry last updated
Mar 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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